Contact lens type amniotic membrane (CLAM) is a promising new approach to using in ophthalmology. It can be used treat range of ocular surface disorders, including dry eye disease, corneal ulcers, and chemical burns. CLAM help reduce inflammation, promote epithelialization wound healing, improve clarity vision. Its ease handling application, combined with its potential therapeutic benefits, mak...

Endothelial keratoplasty (EK) has supplanted the penetrating keratoplasty procedure for corneal endothelial disorders. A review of literature on pre-descemet's EK, that is, a latest iterant in EK is described along with our experiences.

The aim of the present study was to investigate the roles of matrix metalloproteinase 14 (MMP-14) in corneal inflammatory lymphangiogenesis. The expression of MMP-14 in vivo was detected by immunohistochemistry, reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and western blot assays, under various corneal conditions. pCMV-MMP-14 or empty pCMV vectors were injected into mo...

BACKGROUND/AIMS Hyperbaric oxygen (HBO) therapy is used in the treatment of several disorders. Little is known about the effects of HBO treatment on corneal thickness. The aim of this study was to investigate the effect of HBO treatment on central corneal thickness. METHODS Thirty-two subjects (18 males and 14 females, mean age 57.3 ± 16.7 years) undergoing HBO treatment were consecutively en...

PURPOSE To determine the viability and potential usefulness of cryopreserved human primary cultured corneal endothelial cells by characterizing their morphology, gene expression, and ability for genetic modification by the lentiviral vector equine infectious anemia virus (EIAV). METHODS Primary cultured endothelial cells were dissociated from human corneas and grown in organ culture medium. C...

PURPOSE To investigate the prevalence of corneal arcus and its associations. METHODS The Central India Eye and Medical Study was a population-based study performed in rural Central India on 4711 subjects (age, 30+ years). Corneal arcus was assessed in corneal photographs. RESULTS The study included 952 randomly selected participants. Mean body mass index (BMI) was 19.8 ± 3.6 kg/m(2), with 7...

BACKGROUND Ocular trauma or disease may lead to severe corneal opacification and, consequently, severe loss of vision as a result of complete loss of corneal epithelial stem cells. Transplantation of autologous corneal stem-cell sources is an alternative to allograft transplantation and does not require immunosuppression, but it is not possible in many cases in which bilateral disease produces ...

The term corneal dystrophy embraces a heterogenous group of bilateral genetically determined non-inflammatory corneal diseases that are restricted to the cornea. The designation is imprecise but remains in vogue because of its clinical value. Clinically, the corneal dystrophies can be divided into three groups based on the sole or predominant anatomical location of the abnormalities. Some affec...