Correspondence Ronni Wolf, MD Dermatology Unit Kaplan Medical Center 76100 Rechovot Israel E-mail: [email protected] All authors evaluated the patient and histologic specimens, discussed the case, wrote parts of the manuscript, and reviewed and approved the final version of the paper. None of the authors have any relevant conflict of interests. Abstract A 76-year-old man developed a macul...

Introduction: Cutaneous tuberculosis (CTB) is a rare presentation of extrapulmonary tuberculosis (TB) with various clinical manifestations. Tuberculids, a type of CTB, are probably the result of hyperergic immune reaction induced by Mycobacterium tuberculosis. Lichen scrofulosorum (LS) is a rare tuberculid mostly seen in children and young adults with or without other manifestations of tubercul...

Sir, Acute generalized exanthematous pustulosis (AGEP) designates an uncommon, cutaneous reaction characterized by an acute eruption of numerous, small, mostly non-follicular sterile pustules arising on a widespread oedematous erythema; fever above 38 C̊; blood neutrophil count above 7610/l and spontaneous resolution of pustules within 15 days. Typical histopathological findings are subcorneal a...

Hepatitis C virus (HCV) chronically infects 0.5-3% of the world population. A large group of patients develop cirrhosis and its complications. Since 2011, telaprevir and boceprevir are used, improving the disease evolution. One of the main side effects of these drugs is skin eruption. We report a 53-year-old patient with cirrhosis due to HCV who started the classic treatment associated with tel...

BACKGROUND Subacute cutaneous lupus erythematosus (SCLE) is characterized by annular, nonscarring, photodistributed, or papulosquamous lesions. The disease may be idiopathic, drug induced, or drug exacerbated. OBSERVATIONS A 66-year-old woman with a history of hypertension, parkinsonism, rheumatoid arthritis, anxiety and depression, and symptoms of Sjögren syndrome was seen with a 1-month his...

Drug-induced hypersensitivity or Drug Reaction with Eosinophilia and Systemic Symptom (DRESS) is a severe adverse drug-induced reaction. Diagnosing DRESS is challenging due to the diversity of cutaneous eruption and organs involved. Most of the aromatic anticonvulsants, such as phenytoin, phenobarbital, and carbamazepine, can induce DRESS. Culprit drug withdrawal and corticosteroids constituted...

BACKGROUND Hydroxychloroquine sulfate and other antimalarial drugs have been used successfully as adjunctive therapy for patients with cutaneous lesions of dermatomyositis over the past 20 years. An increased incidence of cutaneous reactions to hydroxychloroquine has been postulated to occur in patients with dermatomyositis. OBJECTIVE To determine if adverse cutaneous eruptions due to hydroxy...