background: stem cells from human exfoliated deciduous teeth (shed) have the capability to differentiate into neural cells. neurotrophins including nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3), and neurotrophin-4 (nt-4) have neurogenesis, neurotrophic, or neuroprotective effects and are expressed in developing teeth. the aim of this study was to mea...

dental pulp stem cells (dpscs) can be found within the cell rich zone of dental pulp. these stem cells, under specific stimuli, differentiate into many cell types which have wide therapeutic applications.   the dental stem cells are derived from both deciduous and permanent teeth. the viable dental stem cells are very simple to collect, without any mortality and morbidity. dental pulp stem cell...

the wharton’s jelly of the umbilical cord is believed to be a source of mesenchymal stem cells (mscs) which can be therapeutically applied in degenerative diseases. in this study, we investigated the immunomodulatory effect of umbilical cord derived- mesenchymal stem  cells (uc-mscs) and  bone  marrow-derived-mesenchymal stem  cells (bm-mscs) on differentiation, maturation, and endocytosis of m...

introduction: hyperplastic pulpitis (pulp polyp)tissues contains cells with stem cell properties similar to that of the dental pulp stem cells (dpscs). it has also been shown that cd146 enrichment can homogenize the cultures of dpscs and enhance the colony forming potentials of their cultures. this study determines whether cd146 enrichment can help purifying the stem cells from heterogeneous cu...

background: umbilical cord tissue is a very rich source of mesenchymal stem cells. instead of discarding this source we are banking the tissue along with cord blood for possible future cell based applications. the cord tissue needs to be transported and stored properly in order for it to be good enough for cell isolation at a later date. in this paper we have carried out a validation study to d...

Objective: Arsenic, an environmental pollutant, decreases neuronal migration as well as cellular maturation and inhibits the proliferation of neural progenitor cells. Curcumin has been described as an antioxidant and neuroprotective agent with strong therapeutic potential in some neurological disorders. Human adipose-derived stem cells (hADSCs), a source of multipotent stem cells, can self-rene...

introduction based on previous researches, dental pulp stem cells (dpscs) are easily accessible with limited morbidity after collection. their embryonic origin, from neural crests, explains their multipotency. dpscs are primarily derived from the pulp tissues of the teeth.objective: this study was undertaken to isolate, culture, and characterize two different third molar and first premolar huma...

Objective(s): Cell therapy has provided clinical applications to the treatment of motor neuron diseases. The current obstacle in stem cell therapy is to direct differentiation of stem cells into neurons in the neurodegenerative disorders. Biomaterial scaffolds can improve cell differentiation and are widely used in translational medicine and tissue engineering. The aim...

background:   objective: this study presents an economical and simple co-culture system for pluripotent stem cells generation from neonatal mouse testis   materials and methods: isolated testicular cells were cultured in dmem/f12. characteristics of the isolated cells and obtained es-like cell were immune-cytochemically confirmed by examining the presence of plzf, vimentin, oct4 and nanog prote...