Early diagnosis of sepsis is critical for successful treatment. The clinical value of DcR3 in early diagnosis of sepsis was determined in a dynamic follow-up study. Alterations in plasma levels of DcR3, PCT, CRP, and IL-6 were measured by ELISA and compared among patients with sepsis (n = 134), SIRS (n = 60) and normal adults (n = 50). Correlations and dynamic patterns among the biomarkers, APA...

BACKGROUND We investigated the diagnostic and prognostic utilities of procalcitonin (PCT), B-type natriuretic peptide (BNP), and neutrophil gelatinase-associated lipocalin (NGAL) in critically ill patients with suspected sepsis, for whom sepsis was diagnosed clinically or based on PCT concentrations. METHODS PCT, BNP, and NGAL concentrations were measured in 340 patients and were followed up ...

Background: Sepsis is regarded as a critical clinical status in neonates. Since blood culture is a time-consuming method, the present study was conducted to investigate the serum level of Ferritin, Procalcitonin, and CRP in the peripheral blood of term neonates suspected with sepsis to have a quicker diagnosis for the disease. Methods: In the pres...

Neonatal sepsis can be classified into two subtypes depending upon whether the onset of symptoms is before 72 hours of life (early-onset neonatal sepsis-EONS) or later (late-onset neonatal sepsis-LONS). These definitions have contributed greatly to diagnosis and treatment by identifying which microorganisms are likely to be responsible for sepsis during these periods and the expected outcomes o...

Background: Diagnosis of sepsis in burn patients remains difficult for various reasons. One major problem is the definition itself. Therefore, previous and current definitions are a matter ongoing validation, but well-defined consensus on which clinical laboratory parameters to incorporate such lacking. The aim present study was compare incidence time-related occurrence septic events according ...

Diagnosis of sepsis in critically ill patients is important to reduce morbidity and mortality. The present study was conducted to determine the role of serum leptin in the early diagnosis of sepsis and to establish a diagnostic model for sepsis. A retrospective study was conducted of 331 patients from an intensive care unit. All patients underwent consistent blood collection at 6:00 a.m. every ...

SEPSIS is a complex clinical syndrome involving both infection and a deleterious host immune response. Actue Kidney Injury (AKI) is a frequent and serious complication of sepsis in Intensive Care Unitpatient (ICU). Despite recent impressive advances in the pathophysiology, diagnostic procedures, and appropriate therapeutic interventions in sepsis, sepsis-induced AKI fails to reduce the overwhel...

Abstract To investigate whether serum‐soluble PD‐L1 (sPD‐L1) is a potential biomarker for identifying sepsis. This study enrolled 64 septic patients, 29 patients with acute appendicitis, 33 pancreatitis and 30 healthy volunteers. Sepsis was defined according to the 3.0 criteria.[1] The associated clinical parameters were recorded, blood samples collected on first day of diagnosis, serum sPD‐L1 ...