The angular resolution of many commercial imaging systems is limited, not by diffraction or optical aberrations, but by pixilation effects. Multiaperture imaging has previously demonstrated the potential for super-resolution (SR) imaging using a lenslet array and single detector array. We describe the practical demonstration of SR imaging using an array of 25 independent commercial-off-the-shel...

We present a generic sub-diffraction-limited imaging method - photobleaching imprinting microscopy (PIM) - for biological fluorescence imaging. A lateral resolution of 110 nm was measured, more than a twofold improvement over the optical diffraction limit. Unlike other super-resolution imaging techniques, PIM does not require complicated illumination modules or specific fluorescent dyes. PIM is...

Laser Scanning Microscopy Techniques such as Confocal Microscopy, Two Photon Excitation Microscopy, Second Harmonic Generation Microscopy or Fluorescence Lifetime Imaging have been successfully employed to date for imaging skin cancer. However, the resolution that such techniques can provide is limited by diffraction, which prevents accurately imaging (and differentiating) optical details sized...

Automated classification of biological cells according to their 3D morphology is highly desired in a flow cytometer setting. We have investigated this possibility experimentally and numerically using a diffraction imaging approach. A fast image analysis software based on the gray level co-occurrence matrix (GLCM) algorithm has been developed to extract feature parameters from measured diffracti...

Since the first demonstration of coherent diffraction microscopy in 1999, this lensless imaging technique has been experimentally refined by continued developments. Here, instrumentation and experimental procedures for measuring oversampled diffraction patterns from non-crystalline specimens using an undulator beamline (BL29XUL) at SPring-8 are presented. In addition, detailed post-experimental...

Ghost imaging and ghost diffraction can be realized by using the spatial correlations between signal and idler photons produced by spontaneous parametric down-conversion. If an object is placed in the signal (idler) path, the spatial correlations between the transmitted photons as measured by a single, non-imaging, "bucket" detector and a scanning detector placed in the idler (signal) path can ...

Water-mediated bond formation: The structure of the peptide GPG-NH2 has been investigated in aqueous solution to understand the role of water in the formation of a β-turn. Using a combination of neutron diffraction enhanced by isotopic substitution, NMR spectroscopy, and computer simulations, it was found that water is an essential component to initiate folding in solution.

Coherent diffraction microscopy (CDM) is a potential approach to image micromaterials at atomic resolution without crystals. Due the lack of high-angle scattering, achieved limited several nanometers. Small-angle scattering allows researchers reveal high-resolution 3D structures specimens by fitting 1D signals. However, prerequisite models and non-unique solutions restrict general specimens. Un...

Abstract A high frequency asymptotic technique based on the Uniform Theory of Diffraction (UTD) is employed for building interior imaging. The analysis is implemented using a set of heuristic diffraction coefficients for dielectric wedges and corners with ray-tracing that accounts for multiple through-wall interactions within building. Comparisons with experimental data of the images formed by ...