Zebrafish (Danio rerio) are an excellent vertebrate model for studying heart development, regeneration and cardiotoxicity. Zebrafish embryos exposed during the temporal window of epicardium development to the aryl hydrocarbon receptor (AHR) agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exhibit severe heart malformations. TCDD exposure prevents both proepicardial organ (PE) and epicardium d...

Background: The conceptualization of the transfer of embryos between the individuals who created them to one or more recipients for family-building is hotly contested – particularly as regards whether the practice should be most appropriately considered to be “donation” or “adoption”. This paper examines this debate, considering the research carried out on the intentions and decisions of those ...

Abstract* Introduction: Visual system have been considered as among important sensory system in animals’ life span and their survival is closely related to normal visual system functioning. Since in previous studies it have been revealed that morphine consumption during pregnancy could lead to defect and delay in nervous system development in the embryos, in the present study, changes induc...

Genetic aberrations are commonly seen in human preimplantation embryos. Non-disjunction and premature division of a chromosome are common in both meiosis and mitosis divisions. The expected result for meiotic aneuploidies is full aneuploidy in the later stages whereas mosaicism is the most frequent event in the cleavage and blastocyst stages. The main causes for mosaicism are post-zygotic event...

This paper presents mental disorders of the Serbs caused by war actions from Balkan Wars to wars at end last century. Both stress/traumatic events (war actions, camps, refugees) and changes in forms tremors First World War, partisan hysteria post-traumatic stress disorder 1990s) are listed. A huge lack data for special categories population is evident War (civil victims, Bosnia Herzegovina) Sec...

Background: Vitrification has been usually used as an assisted reproductive technology in animals and humans. This method needs high concentrations of cryoprotectants that can be toxic with high cooling degrees. Then, vitrification could be change histone modifications such as methylation and acetylation can performance as regulatory controls of gene transcription. So, the purpose of the presen...

Salmonid fish have become important models in evolution and ecology, but possible effects of embryo or larval sex are mostly ignored, probably because morphological gonad formation starts only months after hatching sexual maturation years later. However, recent gene expression studies first observations domestic strains suggest that sex-specific life histories could already start at an embryoni...

Tissue engineering is an increasingly expanding area of research in the cardiovascular field that involves engineering, chemistry, biology and medicine. Cardiac tissue engineering (CTE) aims to regenerate myocardial damage by combining cells, matrix, biological active molecules and physiological stimuli. The rationale behind CTE applications is that in order to regenerate the ventricular wall a...