background: despite numerous developments in the field of assisted reproduction the implantation rate remains low .recent studies suggested that local injury to endometrium in controlled ovarian hyper stimulation cycle improves implantation rate. studies have attempted to intervene in the development of endometrium. objective: the aim of the present study was the exploration of the possibility ...

Dienogest is a synthetic steroid that has been used as a progestogen in contraceptive pills and is currently being studied for its possible clinical use in the treatment of endometriosis. In this study, we investigated the direct effects of dienogest in differentiation and proliferation of human endometrial stromal cells (ESC) in vitro. After 12 days in the presence of oestradiol (10(-8) mol/l)...

The endometrial lining of the human uterus contains a population of phenotypically distinct (CD56(bright), CD16(dim)), tissue-specific, natural killer [uterine natural killer (uNK)] cells that play a key role in the establishment of a successful pregnancy. An increase in the number of endometrial uNK cells occurs when the conceptus implants, and there is a further increase during the early stag...

As the developing blastocyst hatches from the zona pellucida (day 5-6 post fertilization) it has increasing nutritional needs. These are met by the development of an association with the uterine wall into which it implants. A series of synchronized morphological and biochemical changes occur in the embryo and the endometrium. The final product of this is the placenta, a temporary organ that aff...

The aims of the present study were to investigate the effects of a traditional Chinese medicine, Hua Yu Xiao Zheng (HYXZ) decoction, on surgically induced endometriosis in a rat model and to determine the possible underlying regulatory mechanisms. A total of 108 female Sprague-Dawley rats were divided into the control group (n=12) and endometriosis group (EM group; n=96), in which endometriosis...

Retrograde menstruation is postulated as the initiating event in the histogenesis of endometriosis; however, subsequent steps in the pathogenesis of this common disorder remain poorly characterized. The ip accumulation of activated leukocytes and the infiltration of endometriosis lesions by macrophages and T cells are cytological markers of the inflammatory nature of this syndrome. The apparent...

wc studied the correlation between preoperative cervical cytology, postoperative clinicopathologic findings, and sites of metastasis from so surgically staged patients with endometrial carcinoma tliirty-faur patients (68%), liad normal cervical cytology, ami 16(32%) had malignant preoperative cervical cytology. malignant cervical smears were statistically correlated with surgical stage (p = 0.0...

background : endometrial cancer is the most common type of malignancy in female reproductive system and is the fourth common cancer after breast, lungs and colorectal cancers. our aim is to report epidemiology and frequency types of endometrial cancer and clinical staging and grading of this disease. methods : in this description and cross-sectional study, 75 patients with diagnosed endometrial...

Endometrial calcification along with ossification is an uncommon clinical entity. Most of the cases are asymptomatic or present with secondary infertility. Endometrial ossification associated with repeated abortions has been reported very infrequently. Here we report a case of endometrial calcification with ossification  due to retained fetal bony tissue in a 38 year old symptomatic female havi...