HCC cells are characterized by lipiodol deposition (an ethyl Ester of fatty acid of poppy seed containing 37-39% iodine by weight) and emulsification on cell surface, active uptake of lipiodol and prolonged intra-cellular retention for their life span [3]. For percutaneous ethanol lipiodol injection therapy the mixture of 99.5% ethanol and lipiodol at a ratio 10:1 was used with better results t...

Thyroid nodule is one of the most frequently encountered thyroid diseases. High resolution ultrasonography (US) is sensitive and capable of detecting detailed anatomy of thyroid including nodules. Tc-99m thyroid scan is a well established and inexpensive imaging modality for many thyroid disorders. The aim of this study was to detect the effectiveness of percutaneous ethanol injection therapy (...

Behavioral sensitization, defined as a progressive increase in the locomotor stimulant effects elicited by repeated exposure to drugs of abuse, has been used as an animal model for drug craving in humans. The mesoaccumbens dopaminergic system has been proposed to be critically involved in this phenomenon; however, few studies have been designed to systematically investigate the effects of dopam...

Effects of acute ethanol administration on the axoplasmic flow in retinal ganglion cells of rats were studied by intraocular injection of 3H-1-leucine. Ethanol induced a facilitation of the fast axoplasmic flow without affecting the slow axoplasmic flow. Pretreatment with colchicine almost completely eliminated the fast flow in both control and ethanol-treated rats, while cycloheximi...

The purpose of the present study was to determine the acute effects of the anticraving compound acamprosate (calcium acetylhomotaurinate) and the closely related compound homotaurine on ethanol intake and ethanol-stimulated dopamine release in the nucleus accumbens. Male rats were treated with acamprosate (200 or 400 mg/kg intraperitoneally, i.p.) or homotaurine (10, 50, or 100 mg/kg i.p.) 15 m...

Suzuki, T. (Children's Hospital, Buffalo, N.Y.), E. A. Gorzynski, and E. Neter. Separation by ethanol of common and somatic antigens of Enterobacteriaceae. J. Bacteriol. 88:1240-1243. 1964.-Ethanol in a concentration of 85% permits separation from crude culture supernatant fluids of the common enterobacterial antigen and the O antigen, the former being ethanol-soluble, the latter being ethanol-...

The current methods for treatment of cancers are inadequate and more specific methods such as gene therapy are in progress. Among different vehicles, cationic liposomes are frequently used for delivery of genetic material. This investigation aims to prepare and optimize DOTAP cationic liposomes containing an antisense oligonuclotide (AsODN) against protein kinase C alpha in non-small cells lung...

Percutaneous injection of ethanol for treatment of hepatic tumors was first described by Sugiura et al. [1] in 1983. To date, reported experience with the procedure has focused mainly on therapy of hepatocellular carcinoma (HCC) [2-15], with little information available regarding its use in treating metastatic liver lesions [16]. Interest in this technique has grown recently as a possible means...

Objectives Sialorrhea is a common health and psychosocial problem for children with neuromuscular dysfunction secondary to a variety of disorders such as cerebral palsy. Current accepted treatments include the injection of botulinum toxin into the submandibular glands for temporary symptom relief. The purpose of this study is to demonstrate the feasibility of percutaneous ethanol injection for ...