Background: Sub-acute bacterial endocarditis (SBE) rarely presents with features of a small vessel vasculitis. Patients with SBE can also develop multiple serological abnormalities including ANCA. In this report, we present a case of infective endocarditis mimicked ANCA associated glomerulonephritis.Case presentation: A 57-year old male with a clinical picture of rapidly progressive renal failu...

Solid tumors produce both stimulators and inhibitors of angiogenesis. The suppression of metastases by some primary tumors has been attributed to the longer circulatory half-lives of the inhibitors. We propose that intrinsic differences in the physicochemical properties of these regulators may also explain focal suppression of angiogenesis within the primary tumor. We present a mathematical fra...

The observations reported in this paper demonstrate that the intravascular interaction of bacterial and animal protein antigens with homologous antibodies at the site of a tissue made vulnerable by bacterial filtrates induces prompt severe hemorrhagic necrosis in this tissue. In the light of these observations there is offered an explanation of the mechanism underlying focal and skin bacterial ...

Suicide was initiated by several incisions in the skin; the resulting hypovolemia resulted in fatal hypothermia. The unusual autopsy findings in this case due to hypothermia were focal hemorrhages and necrosis of the pancreas and hemorrhagic infarction of the descendending colon. The pathophysiological relevance of the autopsy and histological findings are discussed.

Partial resurfacing of the humeral head with the Hemicap implant has recently become available. Previously, the use of resurfacing in the glenohumeral joint has been used for the treatment of osteoarthritis, cuff tear arthropathy, rheumatoid arthritis, and avascular necrosis. The technique has provided significant pain relief as well as improved function in all pathologies in the available shor...

Encapsulated thyroid tumors of follicular cell origin with high-grade features (EFHG) are unusual neoplasms. In current classification schemes, they are called atypical adenomas or follicular, papillary, or poorly differentiated carcinoma. When noninvasive, EFHG create a major therapeutic/diagnostic dilemma stemming from their rarity, low-stage, high-grade appearance, and lack of long-term foll...