Ubiquitin (Ub)-protein conjugates formed by purified ring-finger or U-box E3s with the E2, UbcH5, resist degradation and disassembly by 26S proteasomes. These chains contain multiple types of Ub forks in which two Ub's are linked to adjacent lysines on the proximal Ub. We tested whether cells contain factors that prevent formation of nondegradable conjugates and whether the forked chains preven...

In adult cases of bilateral cleft lip nasal deformity, an esthetically satisfying result can not be obtained only by manipulation inside the nose with the nasal tip pointing upward. The nasal tip should be made in a more anterior direction for nasal esthetic improvement. Additional tissue beyond the nose is needed, and the forked flap is a useful method in such cases. However, the blood circula...

We consider wave scattering in a forked-shaped waveguide which consists of two finite and one half-infinite intervals having one common vertex. We describe the spectrum of the direct scattering problem and introduce an analogue of the Jost function. In case of the potential which is identically equal to zero on the half-infinite interval, the problem is reduced to a problem of the Regge type. F...

A new allele of the suppressor of forked [su(f)] mutation in Drosophila melanogaster has been found and designated l(l)su(f). It is temperature-sensitive for suppression of forked (/) and has additional temperature-sensitive phenotypes of lethality, female sterility, and abnormal bristle formation at 29 °C. It closely resembles two other conditional alleles of su(f), l{l)su(f) and I{l)ts726. Fe...

The use of grating couplers to couple light near vertically in and out of optical slab or film waveguides represents an attractive method to interface optical fiber to photonic ICs. Newly developed fiber technologies exploiting vector mode polarization and orbital angular momentum (OAM) are inherently threedimensional and interfaces for such beams require the solution of fully general 3D models...

WRN interacting protein 1 (WRNIP1) was originally identified as a protein that interacts with the Werner syndrome responsible gene product (WRN). WRNIP1 is a highly conserved protein from E. coli to humans. Genetic studies in budding yeast suggested that the yeast orthlog of WRNIP1, Mgs1, may function in a DNA damage tolerance pathway that is similar to, but distinct from, the template-switch d...

Transverse sections though Drosophila bristles reveal 7-11 nearly round, plasma membrane-associated bundles of actin filaments. These filaments are hexagonally packed and in a longitudinal section they show a 12-nm periodicity in both the 1.1 and 1.0 views. From earlier studies this periodicity is attributable to cross-links and indicates that the filaments are maximally cross-linked, singed mu...