The unsteady increase in using pharmaceutical opioids is a phenomenon that has existed in human societies for a long time. Furthermore, the ever-growing trend of addiction to opioids affects communities in various economic, social, and cultural aspects. Since abusing pharmaceutical opioids is a complex dynamic problem, it is extremely difficult to recognize the factors influencing this abuse. T...

clopidogrel, an inhibitor of platelet aggregation, selectively inhibits the binding of adenosine diphosphate (adp) to its platelet receptor and the subsequent adp-mediated activation of the glycoprotein gpiib/iiia complex, thereby inhibiting platelet aggregation. oral bioavailability of clopidogrel is very low (less than 50%), due to its poor water solubility. the aim of this investigation was ...

A set of fundamental types of high-level interaction with diagrams is proposed. VIM, a prototype KBS with a 3D cooperative diagram as its user interface illustrates diierent layers of cooperation reeecting this classii-cation. Also a number of ways in which 3D aids such cooperation are identiied.

This extended abstract shows how multiple userclasses can be considered in the link transmission model for dynamic network loading. The method assumes triangular fundamental diagrams for each user-class for which only equal shockwave speed are necessary. The link model is reconsidered; normalizations are link dependent. A simple test case is shown.

We show that Vassiliev invariants separate braids on a closed oriented surface, and we exhibit an universal Vassiliev invariant for these braids in terms of chord diagrams labeled by elements of the fundamental group of the considered surface. 1 Definitions and statements 1.

Genes consist of multiple sequence elements that together encode the functional product and regulate its expression. Despite their fundamental importance, there are few freely available diagrams of gene structure. Presented here are two figures that summarise the different structures found in eukaryotic and prokaryotic genes. Common gene structural elements are colour-coded by their function in...

A fundamental problem in the specification of regulatory privacy policies such as the Health Insurance Portability and Accountability Act (HIPAA) in a computer system is to state the policies precisely, consistent with their high-level intuition. In this paper, we propose UML Sequence Diagrams as a practical tool to graphically express privacy policies. A graphical representation allows decisio...

We show that all versions of Heegaard Floer homology, link and sutured homology are natural. That is, they assign concrete groups to each based 3-manifold, link, balanced manifold, respectively. Furthermore, we functorially isomorphisms (based) diffeomorphisms, this assignment is isotopy invariant. The proof relies on finding a simple generating set for the fundamental group “space diagrams,” t...