The influence of ethylene oxide gas treatment on the in vitro degradation behavior of noncrosslinked, glutaraldehyde crosslinked or hexamethylene diisocyanate crosslinked dermal sheep collagen (DSC) using bacterial collagenase is described. The results obtained were compared with the degradation behavior of either nonsterilized or gamma-sterilized DSC. Upon ethylene oxide sterilization, reactio...

In this study, effect of solvent system on in vitro granisetron HCl release from injectable in situ forming implants were investigated also by means of gamma irradiation sterilization. Implant formulations contain 56% solvent, 38% polymer and 6% drug. For the preparation of the formulations, hydrophobic benzyl benzoate and moderately hydrophobic prophylene carbonate were used as solvents while ...

INTRODUCTION Structurally intact cancellous bone allograft is an attractive tissue form in that it may be filled with osteoinductive agents while providing immediate structural support. Bone allograft tissue is commonly submitted to gamma radiation sterilization of 25-35 kGy to prevent disease transmission from donor to host. In cortical bone, gamma radiation sterilization has been shown to cau...

background: every year millions of dollars are expended to equip and maintain the hospital sterilization centers, and our country is not an exception of this matter. according to this, it is important to use more effective technologies and methods in health system in order to reach more effectiveness and saving in costs. this study was conducted with the aim of evaluating the technology of regi...

Biopolymers, including extracellular matrix proteins and polysaccharides, are used as substrates for cell culture scaffolds in tissue engineering. Ionizing radiation, example with gamma rays or electron beams, is to sterilize materials modify the physical chemical properties of materials. The principles effect ionizing radiation on biopolymers discussed this review article. Among types beams wi...