Recombinant DNA techniques offer the possibility of diagnosing genetic defects directly by analysing DNA itself. This is especially interesting for detecting carriers of recessive defects. In comparison with phenotypic screening with progeny testing or biochemical tests, DNA screening is independent of the time of gene expression and is not influenced by non-genetic effects. If the mutation cau...

Genetics can potentially provide new, species-specific, environmentally friendly methods for mosquito control. Genetic control strategies aim either to suppress target populations or to introduce a harm-reducing novel trait. Different approaches differ considerably in their properties, especially between self-limiting strategies, where the modification has limited persistence, and self-sustaini...

In a tall building with multiple elevators, it is a notoriously di cult task to control the elevators in the most e cient manner [1].The system proposed in this paper contains two key ideas. First, it continuously generates dispatch functions by adaptation to changes in passenger tra c. Second, it tries to reduce passengers' waiting time by multiple elevator allocation when it is expected that ...

The application of the powerful tool molecular biology has made it possible to ask questions not only about hormone production and action but also to characterize many of the receptor molecules that initiate responses to the hormones. We are beginning to understand how cells may regulate the expression of genes and how hormones intervene in regulatory processes to adjust the expression of indiv...

The serological analysis of h u m a n B cell a l loant igens has led to the def ini t ion of a HLAl i nked locus, des ignated H L A D R (1, 2), which codes for h u m a n Ia ant igens, i.e., h u m a n homologues o f m u r i n e Ia antigens. Thus far, 10 allospecificit ies have been assigned to this locus. Evidence has been accumula t ing over the past few years tha t h u m a n Ia ant igens are c...