promethazine hydrochloride, a 5-ht3 antagonist is a powerful antiemetic drug with an oral bioavailability of 25% due to extensive hepatic first pass metabolism and is extremely bitter in taste. to overcome the above draw backs, the present study was carried out to formulate and evaluate fast dissolving taste masked wafers of promethazine hydrochloride for sublingual administration. taste maskin...

low density polyethylene films incorporating different types of organically modified nanoclays were prepared. physical, surface morphology and mechanical properties of the films were analyzed by x-ray diffraction pattern, scanning electron microscopy and tensile strength (ts) and length increase until fracture point (e) parameters, respectively. colony counting method was used to investigate an...

I t is now well established that compatibility for the t t L A antigens between donor and host siblings is generally associated with prolonged excellent function of renal allografts (1-6). Although it may not be possible to identify all of the possible antigens of both segregating series in transplant pairs, nonreactive mixed lymphocyte cultures (MLC) 1 have proven to be excellent predictors of...

This paper investigates briefly the integrated portable reinforcement machine structure design and introduces its design and train of thought. The authors also discuss design methods in engineering applications, as well as how to achieve good heat dissipation effect and enhance the electromagnetic compatibility. The whole machine, with its small volume, good adaptability to environment, and ele...

Chemical cross-linking during spray drying offers the potential for green fabrication of microgels with a rapid stimuli response and good blood compatibility and provides a platform for stimuli-responsive hemicellulose microgels (SRHMGs). The cross-linking reaction occurs rapidly in situ at elevated temperature during spray drying, enabling the production of microgels in a large scale within a ...

A series of glycan-coated quantum dots were prepared to probe the effect of glycan presentation in intracellular localization in HeLa and SV40 epithelial cells. We show that glycan density mostly impacts on cell toxicity, whereas glycan type affects the cell uptake and intracellular localization. Moreover, we show that lactose can act as a "Trojan horse" on bi-functionalized QDs to help intrace...