BACKGROUND Cicatricial alopecia encompasses a diverse group of disorders characterized by the permanent destruction of hair follicles and irreversible hair loss. Follicular unit transplantation was developed in 1994. However, large-scale clinical trials are necessary to study follicular unit transplantation for treating Chinese cicatricial alopecia patients. OBJECTIVE To investigate the effic...

The hair growth cycle consists of three stages known as the anagen (growing), catagen (involution), and telogen (resting) phases. This cyclical growth of hair is regulated by a diversity of growth factors. Although normal expression of both epidermal growth factor and its receptor (EGFR) in the outer root sheath is down-regulated with the completion of follicular growth, here we show that conti...

Primary cicatricial alopecias (PCA) are a diverse group of inflammatory hair disorders of unknown aetiology, clinically characterised by the loss of hair shafts, visible follicular ostia, and variable degrees of scalp inflammation. The hair follicle is the primary target of the disease process and persistent inflammation leads to irreversible damage to the hair follicle’s stem cells. Ultimately...

Hair transplantation surgery is indicated for the patients with male-pattern baldness that is unresponsive to medical treatments. This procedure can be performed in two different approaches. The first one is the strip harvesting technique; a strip of scalp is removed under local anesthesia and then cut into single follicular units, which are then transplanted back into the balding area in order...

Circle hairs (CHs) represent a body hair growth disorder which is characterized by asymptomatic presence of hairs in typical circular or spiraliform arrangement. It is not associated with follicular or inflammatory abnormalities. CHs are rarely reported, probably underestimated, as medical consultation for CH only is rare in practice. It needs to be differentiated from rolled hairs, which is a ...

Androgenetic alopecia is the most common form of hair loss in men. The present study was designed to evaluate the hair growth-promoting activity of a preparation of the Adiantum capillus veneris Linn. (A. capillus veneris Linn.) on albino mice using a testosterone-induced alopecia model. Five groups of albino mice were studied: (A) Testosterone solution only (n=6); (B) Testosterone ‏+ Finasteri...

Androgenetic alopecia is the most common form of hair loss in men. The present study was designed to evaluate the hair growth-promoting activity of a preparation of the Adiantum capillus veneris Linn. (A. capillus veneris Linn.) on albino mice using a testosterone-induced alopecia model. Five groups of albino mice were studied: (A) Testosterone solution only (n=6); (B) Testosterone ‏+ Finasteri...

HAIR growth in the rat occurs in a series of waves, which start ventrally and pass over the flanks to the back (Dry, 1926; Butcher, 1934; Johnson, 1958a). The activity of the hair follicle is cyclic; when the hair has been fully formed there is a period of quiescence during which the dead hair is retained as a 'club'. The duration of the complete cycle varies with site and age, ranging from 24 ...

Introduction: A study was presented in New York 2003 investigating a proposed measurement system, the Hair Volume Index (HVI), for evaluating visual hair density. This based on idea that scalp coverage related to measured volume of given area. The results did not support this contention but rather density correlated with number hairs and shaft diameter, which led development Diame...

BACKGROUND Follicular Unit Transplantation (FUT) is performed using large numbers of naturally occuring individual follicular units obtained by single-strip harvesting and stereo-microscopic dissection. Donor wound scarring from strip excision, although an infrequent complication, still concerns enough patients that an alternative solution is warranted. OBJECTIVE The purpose of this paper is ...