The aim of the study was to quantitatively evaluate B and T lymphocytes and macrophages, based on immunohistochemical investigations (CD43, CD20, CD8 and CD68) of chronic focal and Hashimoto thyroiditis. A new method of image analysis was applied, based on spatial visualization of the antigens reactivity. The obtained results indicated that the numbers of lymphocytes, in particular of cytotoxic...

AIMS To study the distribution of tenascin by immunocytochemistry in autoimmune diseases of the thyroid. METHODS Thyroids from patients with inflammatory lesions of the thyroid (lymphocytic thyroiditis Hashimoto, Grave's disease, thyroiditis DeQuervain) were studied by immunocytochemistry using antibodies against tenascin, collagen III, and collagen IV. RESULTS In autoimmune lymphocytic thy...

chronic venous thromboses were also more common than acute thrombosis. Squizzato et al.1 reported 13 cases of acute cerebral sinus venous thrombosis associated with thyroid disease. The most common etiology of hyperthyroidism was Graves--Basedow disease, and a hypercoagulability state and even vascular compression in the event of large goiter were suggested as a pathogenetic mechanism. In the r...

An increased incidence of Hashimoto thyroiditis has been reported in patients with Turner syndrome, but several cases of Graves' disease were also described ten to 20 years ago. We report the case of a patient with Turner syndrome who developed Graves' disease, 3 years after successful treatment with recombinant human growth hormone (GH). A diagnosis of Graves' disease was made and treatment wi...

objective: hashimoto encephalopathy (he) is known as a steroid-responsive encephalopathy associated with autoimmune thyroiditis or nonvascular inflammation-related autoimmune meningoencephalitis. the average age of onset of he is approximately 50 years; and it is more common in women. the onset of he may be acute or subacute. the course of most he cases is relapsing and remitting, which is simi...

Hashimoto's thyroiditis (HT) is an organ-specific T-cell mediated disease. It is a complex disease, with a strong genetic component. To date, significant progress has been made towards the identification and functional characterization of HT susceptibility genes. In this review, we will summarize the recent advances in our understanding of the genetic input to the pathogenesis of HT.

Undifferentiated carcinoma (also known as anaplastic carcinoma) of the thyroid gland is a highly aggressive malignant neoplasm composed of undifferentiated cells that exhibit immunohistochemical or ultrastructural epithelial differentiation. Nearly all patients report a long history of thyroid gland disease, often goiter or Hashimoto thyroiditis. In most cases, there is a transformation from a ...

Volume 38, no. 10 Collagen Vascular Diseases Disease-related Risk of Vertebral Fracture During Glucocorticoid Treatment of SUGIYAMA NAOKO HASHIMOTO, TAKAFUMI MAYAMA, TOMOAKI TANAKA and TAKAO ICHIRO TATSUNO, SAWAKO SUZUKI, TOMOHIKO YOSHIDA, HIDEKAZU NAGANO, http://www.jrheum.org/content/38/10/2270 J Rheumatol 2011;38;2270-2272 http://www.jrheum.org/alerts 1. Sign up for TOCs and other alerts ht...