Impaired trophoblast cell invasion is believed to be an inciting factor in preeclampsia. Factors driving are incompletely understood. Maternal serum tumor necrosis alpha (TNFα) levels elevated We hypothesized that TNFα influences human cells. treated immortalized first trimester cells (HTR-8/SVneo) with 10 or 100ng/ml for 4 24 hrs. measured protein of soluble fms like tyrosine kinase 1 (sFLT1) ...