OBJECTIVES Genetic mutations and polymorphisms have been correlated with chronic pancreatitis (CP). This study aims to investigate the association of genetic variants of cystic fibrosis transmembrane conductance regulator (CFTR) and serine protease inhibitor Kazal type 1 (SPINK-1) genes and Cathepsin B gene polymorphisms with CP and to associate genetic backgrounds with clinical phenotypes. M...

Human serum paraoxonase (PON) associated with high density lipoprotein (HDL) , has been postulated to have a role in protecting low-density lipoprotein (LDL) against oxidative damage, which has led to the proposal that PON is an anti-atherogenic and anti-inflammatory enzyme. It has genetic polymorphism at the 191 (R ->Q) and two alloenzymes A and B and three phenotypes A, B, and AB. We exa...

genetic improvement programs may improve disease resistance in animal production. the best-characterized genetic control of disease resistance and immune response in animals is the one associated with the major histocompatibility complex (mhc). the ovine lymphocyte antigenof drb1 gene encodes cell surface glycoproteins that initiate immune responses by presenting processed antigenic peptides to...

the genetic diversity of a large number of pistachio genotypes grown in iran is not exactly known. most of the studies on genetic diversity of iranian pistachio varieties are based on morphological characteristics or isozyme markers. in the present study, the genetic diversity of selected pistachio cultivars along with some wild species were evaluated by amplified fragment length polymorphism (...

background: the aim of this study was to understand any association between differentiated thyroid carcinoma (dtc) and ile3434thr xrcc7 gene polymorphism (genbank accession number: rs7830743). dtc is the most prevalent thyroid neoplasm, which includes papillary and follicular cell carcinoma. xrcc7 gene encodes a protein that functions in non-homologous end joining dna repair pathway. non-synony...

materials and methods a case-control study was designed on 91 cases with spontaneous hcv infection clearance and 259 patients with persistent hcv infection as the control group. the rs12979860 snp was assessed as the most common ifnl polymorphism by pcr-rflp method. results distribution of rs12979860 cc genotype in the spontaneous clearance group was around two folds of its distribution in chro...

berari goats are medium sized animals reared mainly for meat purpose. they are predominantly brown and blackish brown in colour with glossy hair and found in vidarbha region of maharashtra state. berari is not a recognized breed but a well established local population of goat which is yet to be fully explored for its phenotypic and genetic aspects. within population genetic variation was examin...

background: it is believed that environmental and genetic factors may be responsible for autism. methylenetetrahydrofolate reductase (mthfr) and its gene polymorphisms have been shown to be implicated as risk factors in autism. objectives: to analyze mthfr c677t polymorphism (rs1801133) in autistic patients. materials and methods: this study was carried out in 2014 and 2015 in northern iran. on...