نتایج جستجو برای: in vitro cytotoxicity

تعداد نتایج: 16984948  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس - دانشکده علوم زیستی 1393

سلول های بنیادی جنینی موشی ابزاری ارزشمند برای انجام مطالعات تمایز سلولی در شرایط in vitro هستند. تمایز سلولی فرایندی جدایی ناپذیر از رشد و نمو موجودات پرسلولی است. در این مطالعه نقش مسیر آپوپتوتیک میتوکندریایی و تغییرات سطح انرژی سلول در فرایند تمایز سلول های بنیادی موشی به کاردیومایوسیت و آپوپتوز بررسی شده است.

ژورنال: مجله دندانپزشکی 2007
 استاد, سید ناصر , ضرابیان, محمد , عباسی, منصوره , محسنی, مهران ,

Background and Aim: Root filling materials are usually in close contact with living tissues. So their biological properties like mutagenicity and cytotoxicity are important. These properties help us determine the potential damage to periapical tissues, or potential DNA mutations, and malignant transformation of the cells. The aim of this study was to evaluate the mutagenicity and cytotoxicity o...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه اصفهان - دانشکده علوم 1390

در پژوهش حاضر با بررسی عصاره های متانولی، هگزانی و پروتئینی تعدادی از گیاهان، به وجود پپتیدها و مواد آلی ضد میکروبی در برخی از آن ها پی برده شد. به منظور امکان سنجی معرفی مواد موٍثره ی موجود در این گیاهان آزمایشات سمیت سلولی و اثر بر روی دو سایتوکاین سیستم ایمنی بدن در مطالعلت in vitro انجام شد. خواص آنتی اکسیدانتی عصاره های گیاهی نیر به دو روش بررسی شد.

Journal: :iranian journal of toxicology 0
محبوبه طاهرخانی mahboubeh taherkhani department of chemistry, takestan branch, islamic azad university, takestan, iran.

background: essential oils are found to have multiple active components which can show in vitro cytotoxic action against various cancerous cell lines. this study reports the in vitro cytotoxic effects of the essential oil from artemisia absinthium l. (asteraceae) growing wild in iran. methods: water-distilled essential oil of a. absinthium collected from ardabil, north-western iran, was examine...

Journal: :acta medica iranica 0
n. sheikh m.r. safari kh. mani kashani m. araghchian f. zeraati

garlic, an antioxidant plant, can react with amino groups of proteins to form schiff bases. as diabetes leads to glycation of various proteins and this in turn has some effects on the structure of proteins and biochemical activity of them, the inhibition of this process seems very vital. for several years researchers in this field have done their best to recognize the antidiabetic compounds. th...

Journal: :jundishapur journal of natural pharmaceutical products 0
reza taherkhani infectious and tropical diseases research center, ahvaz jundishapour university of medical sciences, ahvaz, ir iran; department of medical virology, school of medicine, ahvaz jundishapur university of medical sciences, ahvaz, ir iran fatemeh farshadpour infectious and tropical diseases research center, ahvaz jundishapour university of medical sciences, ahvaz, ir iran; department of medical virology, school of medicine, ahvaz jundishapur university of medical sciences, ahvaz, ir iran manoochehr makvandi infectious and tropical diseases research center, ahvaz jundishapour university of medical sciences, ahvaz, ir iran; department of medical virology, school of medicine, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; department of medical virology, school of medicine, ahvaz jundishapur university of medical sciences, ahvaz, ir iran. tel: +98-9166181683, fax: +98-6113738313

conclusions these results indicate that a. kellalensis extracts exert potent anti-rotaviral activity only after viral adsorption. the two extracts from a. kellalensis showed a good selectivity index. also these results suggest that extracts prepared from the flowers of a. kellalensis may be potential anti-rotaviral agents in vivo and be useful in veterinary medicine. background achillea kellale...

Journal: :jundishapur journal of natural pharmaceutical products 0
azita hedayati department of periodontics, shiraz university of medical sciences, shiraz, ir iran; department of periodontics, shiraz university of medical sciences, shiraz, ir iran. tel: +98-7116275784, fax: +98-7116275784 hengameh khosropanah department of periodontics, shiraz university of medical sciences, shiraz, ir iran abdollah bazargani department of bacteriology and virology, shiraz university of medical sciences, shiraz, ir iran molud abed department of periodontics, shiraz university of medical sciences, shiraz, ir iran amir emami department of bacteriology and virology, shiraz university of medical sciences, shiraz, ir iran

materials and methods the subjects included 27 male and 3 female patients with advanced chronic periodontitis. the mean age of the patients was 47.6 ± 2.0 years old. p. gingivalis was isolated from the samples and identified by various diagnostic tests, including gram staining, indol test, and fluorescent test. minimum inhibitory concentration (mic) of the essential oil against isolated p. ging...

Journal: :research in pharmaceutical sciences 0

recently, several studies have shown that the metal-fluoroquinolone complexes have more antibacterial and cytotoxic effects in comparison with free fluoroquinolones. these results may introduce new drugs for chemotherapy with fewer side effects. in this work a bidentated zinc (ii) complex with ofloxacin (ozc) was synthesized and cytotoxicity activities and dna binding of the resulted complex wa...

The biological application of nanoparticles (NPs) is a rapidly developing area of nanotechnology that raises new possibilities in the treatment of human cancers. The cytotoxicity was evaluated by MTT and LDH assays. The apoptotic effect of free ICD-85 and ICD-85 NPs on HeLa cells was assessed using caspase-8 colorimetric assay. The MTT assay showed that ICD-85 NPs could enhance the in-vitro cyt...

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