There are obvious analogies between disorders of intestinal amino-acid absorption and the more familiar anomalies of carbohydrate absorption. Both monosaccharides and free amino acids are important water-soluble nutrients which must be transported across the lipid-containing intestinal cell membrane by specific active transport processes involving concentration of the compounds within the cell ...

The intestinal epithelium is equipped with sensing receptor mechanisms that interact with luminal microorganisms and nutrients to regulate barrier function and gut immune responses, thereby maintaining intestinal homeostasis. Herein, we clarify the role of the extracellular calcium-sensing receptor (CaSR) using intestinal epithelium-specific Casr(-/-) mice. Epithelial CaSR deficiency diminished...

The intestinal epithelial barrier is indispensable to our immune system. Defects in this barrier function have been observed in intestinal disorders such as inflammatory bowel diseases, food allergies, and celiac diseases. Therefore, the modulation of the barrier function is currently viewed as a potentially positive pharmacological outcome. This review describes a unique peptide, Asn-Pro-Trp- ...

BACKGROUND & AIMS Evaluation of small bowel motility by intestinal manometry is invasive and requires expertise for interpretation. Our aim was to use capsule technology for evaluation of small bowel motor function based on a fully computerized image analysis program. METHODS Thirty-six consecutive patients with severe intestinal motor disorders (19 fulfilling manometric criteria of intestina...

Primary intestinal lymphangiectasia or Waldmann's disease is an uncommon cause of protein losing enteropathy with an unknown etiology and is usually diagnosed during childhood. It is characterized by dilation and leakage of intestinal lymph vessels leading to hypoalbuminemia, hypogammaglobulinemia and lymphopenia. Differential diagnosis should include erosive and non-erosive gastrointestinal di...

Background: Cryptosporidiumis known as an opportunist disease-causing agent in man in recent decades. It causes diarrhea and intestinal disorders in the immune deficit and immune competent individuals. This study was aimed to investigate the clinical characteristics of HIV/AIDS patients withcryptosporidiosisinfection. Methods: This cross...

Lactobacillus plantarum has potential applications and health benefits. This comprehensive literature review highlights the probiotic properties of L. its ability to withstand adverse conditions adhere intestinal epithelium. It immense in food industry, focusing on fermentation, preservation, bioactive compound production. Furthermore, impact human health, including role modulating gut microbio...