background and aims: from the past studies, it has been proved that consumption of heavy metals by humans may cause several chronicle problems like cancer, kidney and liver damage, high blood pressure and low blood pressure problems and etc. so, it has become very crucial to remove these heavy metals from industrial wastewater. the aim of this study was to find out a low cost and easy available...

BACKGROUND Heavy-ion therapy has an advantage over conventional radiotherapy due to its superb biological effectiveness and dose conformity in cancer therapy. It could be a potential alternate approach for hydatid cyst treatment. However, there is no information currently available on the cellular and molecular basis for heavy-ion irradiation induced cell death in cystic echinococcosis. METHO...

Heavy carbon-ion beam therapy has revealed several potential advantages over X-rays. Heavy-ion therapy has been applied for various solid tumors including esophageal squamous cell carcinoma (SCC). Although the local control rate of carbon ion radiotherapy for esophageal cancer has revealed better rates than that of conventional radiotherapy, some patients have shown resistance to the treatment....

An ion-optical based fast adaptation of ion beam range for the treatment of moving targets with beam tracking was investigated. The method employs a deflection of the ion beam on a small single wedge-degrader positioned between two bending magnets for range adaptation [1, 2]. A prototype system was implemented at the therapy beam line at GSI and beam parameters of energy-adapted beams were char...

an enzyme electrode was developed using the enzyme sulfite oxidase (ec1.8.3.1) immobilized onto pig intestine. hydrogen peroxide produced was monitored amperometrically. all experimental parameters such as ph, temperature, buffer constituent concentration, were thoroughly investigated and optimized when appropriate. the response to sulfite concentration was linear in the range 5.2´10-6 to 1.02´...

Radiation therapy is an integral part of the multi disciplinary therapy of lung cancer. Genetic changes and the specific tumor microenvironment favour therapy resistance of tumor cells. Clinical studies suggest that particle irradiation with carbon ions may improve the therapy response of solid tumors compared to photon radiation [1]. Occurrence of therapy resistance is related to secretion of ...

called the “Center”) was established in 1993 when NIRS completed construction of the HIMAC. Since then it has been carrying out clinical, biological and physics research using heavy ions generated from the HIMAC. After accumulating clinical experiences of carbon ion radiotherapy (C-ion RT) in various types of malignant tumors, the Center was successful in obtaining approval from the Ministry of...

In the human genome more than 400 genes encode ion channels, which are transmembrane proteins mediating ion fluxes across membranes. Being expressed in all cell types, they are involved in almost all physiological processes, including sense perception, neurotransmission, muscle contraction, secretion, immune response, cell proliferation, and differentiation. Due to the widespread tissue distrib...

BACKGROUND In view of the continued increase in the number of hadron (i.e. neutron, proton and light or heavy ion) therapy (HT) centres we performed a systematic literature review to identify reports of the efficacy of HT. METHODS Eleven databases were searched systematically. No limit was applied to language or study design. Established experts were contacted for unpublished data. Data on ou...