1. Thirty-five pigs were fitted with single re-entrant cannulas in either the duodenum, jejunum or ileum. A further twenty-four pigs were used in a conventional digestibility trial. 2. Methods for collecting, sampling and returning digesta were developed. 3. A 'practical-type' diet and two purfied diets were used, fed twice daily. 4. Flow and pH of digesta were measured hourly in the duodenum a...

1. Proteolytic (substrate nitrocasein), tripeptidase (substrate glycylglycylgly-cine) and aminopeptidase (substrate leucyl-beta-naphthylamide) activities were studied in homogenates of jejunal and ileal mucosa of 7-, 10-, 14-, 21-, 35- and 60-day-old rats. 2. Proteolytic activity was practically the same in jejunum of 7-, 10-, 14- and 21-day-old rats, but after day 21 a significant increase was...

Stimulation of Ca2+ absorption can counteract hypocalcemia at the onset lactation. The plant bioactive lipid compound (PBLC) menthol is an agonist for nonselective cation channels transient receptor potential (TRP) family. It acutely stimulated in ruminal epithelia nonadapted animals ex vivo and caused higher plasma concentrations cows sheep vivo. To elucidate pathway by which feeding increases...

Gastrointestinal stromal tumors (GISTs) of the duodenum are relatively rare and difficult to diagnose in early stage because it lacks pathognomonic symptoms. Here, we report a case of multiple GISTs involving the third and fourth portions of the duodenum and proximal jejunum, which were revealed in an emergent laparotomy. A 40-year-old, previously healthy man was referred to the Emergency Depar...

Jejunum and ileum from vitamin D-deficient rats actively secreted calcium when studied in vitro, while duodenum from these animals actively absorbed calcium. Acute repletion with a single physiologic dose of 25-hydroxyvitamin D3 (25-OH D3) (15 i.u.) increased calcium absorption in duodenum and ileum but had no effect on jejunum. Studies of the distribution of 25-OH D3 and its metabolites in the...

Introduction: Considering the long traditional history of anti-inflammatory and anti-spasmodic effects of Matricria spices on the gastrointestinal system, the present study aimed to investigate the role of calcium channels and Histamine receptors in the inhibitory effects of hydroalcoholic dry extract of German chamomile (Matricaria recutita L.) on the isolated rabbit jejunum. Methods: All ...

Background and aims: There is increasing evidence implicating intestinal immune responses to dietary proteins in the pathogenesis of type 1 autoimmune diabetes (T1D). Here we investigated the association between intestinal pathology and dietary factors in T1D by examining the mucosal architecture in the BB rat model. Methods: BB control (BBc) and diabetes prone (BBdp) rats were fed either a dia...