Isotonic regression is a useful tool to investigate the relationship between a quantitative covariate and a time-to-event outcome. The resulting non-parametric model is a monotonic step function of a covariate X and the steps can be viewed as change points in the underlying hazard function. However, when there are too many steps, over-fitting can occur and further reduction is desirable. We pro...

Few would refute the importance of harnessing organizational knowledge for reuse, learning, and process improvement. The key to achieving this is by retaining existing knowledge in a central repository so that this knowledge can be shared and reused. In this way, precious resources need not be re-employed where prior work has already been done before. Many organizations are aware that technolog...

An increasingly relevant theme for knowledge-based systems is how to model and use a large and complex knowledge domain. On the one hand, this involves developing new ideas on a modular construction of a knowledge base and, on the other hand, an appropriate architecture of a knowledge-based system that takes account of such a modular knowledge base. In the HYPERCON project we conceptualize a co...

The problem of comparing and matching different learners’ knowledge arises when assessment systems use a one-dimensional numerical value to represent “knowledge level”. Such assessment systems may measure inconsistently because they estimate this level differently and inadequately. The multi-dimensional competency model called COMpetence-Based learner knowledge for personalized Assessment (COMB...

Design and engineering are knowledge intensive processes. Large amounts of different types of knowledge are needed in real world applications. An essential pre–requisite for the usage and re–use of this knowledge is an adequate modeling framework which describes the role or roles of each ’piece’ of knowledge in the overall context. The MOKA framework has been developed as a generic scheme for d...

introduction: much of activities in today's world are based on information and less time is dedicated to gain experience and knowledge. therefore, different organizations compete based on their knowledge. in such a situation, knowledge management provides necessary tools to improve the performance of human resources and creates competitive advantages. this paper sought to determine the relation...

extended abstract introduction economic development is a favorable aim for all nations and meeting this aim requires a good understanding of variables taking part in this process. the role of entrepreneurship in economic development has been mentioned by many authors as an important one. although creating jobs is a function of entrepreneurial process, but it is not the only one. entrepreneursh...