introduction: failure to achieve adequate and profound anesthesia in teeth with acute pulp inflammation is a common condition during emergency visits in root canal therapy. many different anesthetic solutions such as morphine and capsaicin have accordingly been examined. mannitol­ an alcoholic sugar with high osmotic pressure level- is applicated for reducing intracranial and post retinal press...

STUDY OBJECTIVE The study aims to evaluate the efficacy and safety of intranasal lidocaine administration for migraine treatment. METHODS This single-center, double-blind, randomized, controlled trial was conducted in a tertiary care emergency department. Included patients met the migraine criteria of the International Headache Society. Patients were randomized to intranasal lidocaine or sali...

clinical studies suggest that essential oil of eugenia caryophyllata (clove) buds (eoec) is efficacious in the treatment of dental pain. in the present study, we investigated the analgesic and local anesthetic effects of eoec and its possible mechanisms of action in acute corneal pain in rats. eoec was extracted by hydro-distillation in a clevenger type apparatus from clove buds. the acute corn...

Introduction: Nowadays, spinal anesthesia is associated with few complications in many surgical practices especially the elective caesarean which is taken as a suitable replacement for general anesthesia. Different drugs are used for spinal anesthesia. This study aims to compare lidocaine 5% in combination with meperidine 5% plus lidocaine 5% for spinal anesthesia in non-emergency cesarean pati...

We have been using preoperative infiltration with lidocaine and epinephrine in breast reduction since 1984. The injection fluid we use is a 0.5% lidocaine solution with 1:400,000 epinephrine, as opposed to the 0.25% prilocaine solution with 1:800,000 epinephrine used by the authors. We inject 60 ml of this solution into each breast, 15 minutes before the beginning of the operation, in the sites...

This blinded, randomized experimental study was designed to evaluate the analgesic effects of adding epinephrine or xylazine to lidocaine solution for brachial plexus block (BPB) in sheep. Nine healthy, fat-tailed female lambs (26.6 ± 1.5 kg) were randomly allocated into three groups: lidocaine 2%, 5 mg kg-1 (LID, n = 6), lidocaine (5 mg kg-1) with epinephrine 5 µg mL...

Over the last decade, there has been increasing interest in minimally invasive cosmetic treatments, especially for facial rejuvenation. Next to botulinum toxin injection, the injection of soft tissue fillers is the second most frequent minimally invasive procedure performed in the USA. Hyaluronic acid (HA) is the most commonly used dermal filler. One of patients' main concerns about filler inje...