Hydrolysis and precipitation are the key processes that determine coagulation performance of inorganic metal salts. The valence concentration salts, ligands, solution pH all influence performance. In order to get a full picture on pros cons various salts as coagulants, this paper conducted thermodynamic equilibrium calculations experiments analyze verify hydrolysis-precipitation a...

The use of ylides of P, N, As or S as ligands toward transition metals is still a very active research area in organometallic chemistry. This fact is mainly due to the nucleophilic character of the ylides and to their particular bonding properties and coordination modes. They can behave as monodentate or bidentate –chelate or bridging– species, they can be used as chiral auxiliary reagents, the...

Vasoactive effects of soluble matrix proteins and integrin-binding peptides on arterioles are mediated by a v b 3 and a 5 b 1 integrins. To examine the underlying mechanisms, we measured L-type Ca 2 1 channel current in arteriolar smooth muscle cells in response to integrin ligands. Whole-cell, inward Ba 2 1 currents were inhibited after application of soluble cyclic RGD peptide, vitronectin (V...

background: although there is convincing data in support of the effectiveness of hyperthermia in tumor therapy, the molecular mechanisms underlying the clinical effects of hyperthermia are still poorly understood. objective: to investigate natural killer (nk) cell cytotoxicity against heat-treated sw-872 and hela tumor cell lines. methods: nkg2d ligands and hla class i transcription were examin...

The hydrosilylation of alkynes is one the most attractive and, at same time, challenging catalytic transformations, usually demanding use noble transition metals. We describe a system, based on cobalt(0) complex and bulky N-heterocyclic carbene (NHC) ligands, permitting highly effective broad scope silanes. application NHC ligands allowed decrease in amount cobalt necessary for an reaction run ...

Studying the interaction of pharmaceutical ionic liquids with human serum albumin (HSA) can help investigating whether or not ionic liquid formation can enhance pharmacological profile of the discrete ingredients. In this respect, in the present work, the interactions of Benzalkonium Ibuprofenate, as a well-known active pharmaceutical ionic liquid, Benzalkonium Chloride, and also Sodium Ibuprof...

The complexation of Cd2+ by diallyl disulfide (DADS) and diallyl sulfide (DAS) has been studied by differential pulse voltammetry. Stability constants, (log β), of the 1:1 (PbL) and 1:2 (PbL2) complexes, where L = ligand, were found to be in the range of ca. 5.8 - 6.2 and 9.6 -10.6, respectively. Complex formation is accompanied with a significant decrease in the peak current and the shift of t...

Zinc sulphate is currently used for treatment of zinc deficiency. Its uptake by the body is poor, necessitating the administration of high doses. This leads to a range of unpleasant side effects. In order to increase the bioavailability of zinc, several zinc complexes have been designed and synthesized using bidentate ligands of hydroxypyranones and hydroxypyridinones. Elemental analysis in eac...

Abstract We previously developed TANTIGEN, a comprehensive online database cataloging more than 1000 T cell epitopes and HLA ligands from 292 tumor antigens. In TANTIGEN 2.0, we significantly expanded coverage in both immune response targets (T ligands) It catalogs 4,296 antigen variants 403 unique antigens 1500 ligands. also included neoantigens, class of generated through mutations resulting ...