Background: Osteoporosis, or porous bone, is a disease characterized by low bone mass density (BMD) and structural deterioration of bone tissue, leading to bone fragility and increased risk of hip, spine, and wrist fractures. There are numerous risk factors for osteoporosis. While many of these factors are non-genetic in nature, there is a definite genetic component responsible for this condi...

Background: During lactation, metabolic changes in the bone in different areas of the body may affect the amount of bone mineral density.The aim of this study was to determine the relationship between breastfeeding and bone mineral density in women. Materials and Methods:  In this study, articles were searched at Cochran, Medline (via PubMed), Scopus, and Web of Science databases until June 201...

background different clinical and epidemiological studies using dual-energy x-ray absorptiometry have shown an increased prevalence of low bone mineral density in patients with inflammatory bowel diseases.the aim of this study was to assess the correlation between bone density and the disease activity in patients with ulcerative colitis. methods in this cross-sectional study, 52 patients with u...

Background: Calcium supplements increase bone mass in children, but the effect does not persist once supplementation is discontinued. Objective: The objective of this study was to determine whether milk intake during childhood and adolescence, when controlled for current calcium intake, is associated with adult bone mass (ie, bone mineral content), bone mineral density, and the incidence of ost...

With the advent of effective antiretroviral therapy (ART), the recognition and management of long-term complications of HIV infection and ART are increasingly important for HIV physicians. Low bone mineral density (BMD) is more common in those with HIV infection and this review will outline therapeutic options for the management of low bone mineral density relevant to HIV-infected populations.

Background: The purpose of this study was to evaluate long-term changes in bone density profile among survivors of childhood acute lymphoblastic leukemia. Patients and Methods: This was a 5 year prospective study comprised of thirty-one survivors of childhood acute lymphoblastic leukemia with a mean age of 11.8 (4.6) years, who completed therapy at least 1 year previously (according to the ...

OBJECTIVE To determine the effectiveness of vitamin D supplementation for improving bone mineral density in children and adolescents and if effects vary with factors such as vitamin D dose and vitamin D status. DESIGN Systematic review and meta-analysis. DATA SOURCES Cochrane Central Register of Controlled Trials, Medline (1966 to present), Embase (1980 to present), CINAHL (1982 to present)...

Osteoporosis, associated with low BMD, is a public health problem. Peak bone mass (PBM) is influenced by genetics, nutrition, body weight and physical activity, with 90% of PBM obtained by age 18 years. Recent research challenges the belief that obesity protects against low BMD. In a study of overweight and obese adults, researchers noted that overweight status was neutral or protective of BMD,...

An inadequate and imbalanced intake of protein and energy results in protein-energy malnutrition (PEM). It is known that bone mineral density and serum magnesium levels are low in malnourished children. However, the roles of serum magnesium and endothelin-1 (ET-1) levels in the pathophysiology of bone mineralization are obscure. Thus, the relationships between serum magnesium and ET-1 levels an...

OBJECTIVE Joint hypermobility can be associated with benign musculoskeletal pain. The relation between hypermobility and low bone mineral density is still unknown. Osteoporosis can be observed in some genetic syndromes associated with joint hypermobility. The aim of our study was to detect the possible relation between joint hypermobility, benign musculoskeletal pain and bone mineral density in...