OBJECTIVE The purpose of this study was to investigate the relationship between nitric oxide degradation products (nitrate and nitrite) levels and megaloblastic anemia which is treated with cyalocobalamin. METHODS A total of 30 patients with megaloblastic anemia (16 Male, 14 Female) were included in the study. Cyanocobalamin was administered (1.000 µg/day intramuscularly) until the reticulocy...

Morphological abnormalities of the haemopoietic cells in pernicious anaemia have been well known for many years, but it is only recently that attention has been drawn to abnormalities in the epithelial cells. Graham and Rheault (1954) studied the buccal epithelial cells in gastric washings and showed that there was general enlargement of the cytoplasm and of the nucleus, the presence of some ce...

deficiency of vitamin b12 and/or folic acid as a cause of pyrexia, though known, is rarely reported in literature. we aimed to report a case in a 51 year old woman, who presented with fever and pancytopenia and was diagnosed to have megaloblastic anemia secondary to vitamin b12 and folate deficiency. the pyrexia subsided following the intramuscular injection of vitamin b12 and oral folic acid a...