Introduction: Melasma is the main cause of facial hyperchromia and has a signifi cant psychosocial impact. Wood ́s lamp has been a useful device to estimate the depth of melanin determined by light-induced fl uorescence. A dermoscope enables a clear visualization of pigments distribution, and the color variation of melanin will depend on its location within the skin. Objective: Evaluate the clas...

The aim of the present study was to evaluate the efficacy and safety of lignin peroxidase (LIP) as a skin-lightening agent in patients with melasma. A self-controlled clinical study was performed in 31 women who had melasma on both sides of the face. This study involved 8 weeks of a full-face product treatment. The skin color was measured at days 0, 7, 28 and 56 using a chromameter on the foreh...

Melasma is a cosmetic disorder with profound psychological impact. Multiple therapies are available for melasma but no therapy the gold standard. The most of patients suffer from relapses and recurrences which force patient to opt over-the-counter medications containing topical steroids or indigenous medications. Use these has led emergence complicated cases refractory treatment. Along hyperpig...

Background Melasma is a common, chronic skin condition of hyperpigmentation involving the appearance symmetric and irregular light brown macules patches, mainly on sun exposed head neck. Though pathogenesis not fully understood, hyperfunctional melanocytes are known to deposit excess melanin in epidermis dermis. Known risk factors or triggers include genetic influence, hormonal ultraviolet radi...

The aim of this study was to determine the impact of melasma on quality of life (QoL) using the dermatology life quality index (DLQI) questionnaire in a group of outpatients. This study is questionnairebased. A total of 101 Turkish women suffering from melasma, who themselves were able to understand and complete the Turkish version of the DLQI questionnaire, were enrolled. This questionnaire in...

Estrogens are widely used in hormone replacement therapy, gynecology, urogynecology and rarely in dermatology. Non-therapeutic use of estrogens is very widespread. Estrogens are used as contraceptives, which cause a lot of serious side effects. A common clinical problem is skin hyperpigmentation (melasma), occurring mainly in women who take contraceptives with high doses of estrogens. But low d...

melasma is a common acquired skin disorder. while different treatments are currently being used, in many cases it is refractory to treatment. according to the effects of topical steroids in decreasing skin pigmentation, we studied the efficacy of this new method for treatment of melasma. a total of 42 women with facial melasma, admitted to the department of dermatology of hamadan, were enrolled...

introduction: ablative and nonablative lasers have been used to treat melasma. we aimed to assess and compare the combining q-switched nd:yag laser (qsnyl) and fractional erbium:yag laser (feyl) with qsnyl alone in treatment of melasma. methods: this randomized controlled clinical trial was performed in our research center during 2013-2014. women with melasma and without a history of keloid for...