Vancomycin-sensitive, -intermediate, and -heterointermediate methicillin-resistant Staphylococcus aureus isolates were tested by using E-tests to explore the interaction of methicillin and vancomycin. For the vancomycin-intermediate and -heterointermediate strains both drugs showed antagonism at concentrations below their MICs but synergy at methicillin concentrations near the MIC. This propert...

BACKGROUND In Latin America, few studies have been carried out on methicillin-resistant Staphylococcus aureus carriage in the pediatric population. We conducted a survey of nasal S. aureus carriage in neonates and in children attending the pediatric outpatient clinics in a large Brazilian city with high antimicrobial consumption. METHODS Pernasal swabs of neonates were collected upon admissio...

PURPOSE The purpose of this study is to characterize the bacterial flora of the ocular and periocular surface in cataract surgery patients and to determine the prevalence of methicillin resistance among staphylococcal isolates obtained from health care workers (HCWs) and non-HCWs. METHODS In this prospective, multicenter, case series study, eyelid and conjunctival cultures were obtained from ...

patients and methods: all samples sent to the lab were routinely processed according to standard microbiological procedures and the cultures yielding growth of cons were selected for the study. all samples containing cons collected over a 2 year-period, were included irrespective of patients' age and gender. the antibiogram of the organisms was recorded according to clsi guidelines and the rati...

The GenomEra MRSA/SA assay (Abacus Diagnostica, Turku, Finland) is the first commercial homogeneous PCR assay using thermally stable, intrinsically fluorescent time-resolved fluorometric (TRF) labels resistant to autofluorescence and other background effects. This fully automated closed tube PCR assay simultaneously detects Staphylococcus aureus specific DNA and the mecA gene within 50 min. It ...

Objective(s): The novel healing choices for handling of infections due to multidrug resistant Staphylococcus aureus are reguired. HAMLET has been reported to be able to sensitize bacterial pathogens to traditional antimicrobial agents. The aim was to assess wound healing activity of methicillin in presence of HAMLET in methicillin resistant S. aureus (MRSA) infected wounds. Materials and Method...

Background: Methicillin-resistant Staphylococcus aureus (MRSA) is resistant to most antibiotics and is an important pathogen of nosocomial infections. The prevalence of community (CA-MRSA) and hospital acquired methicillin-resistant S. aureus (HA-MRSA) infection is increased. In this study we investigated the frequency of MRSA colonization and its antibiotic susceptibility in students of Rafsan...

OBJECTIVES Methicillin-resistant Staphylococcus is a growing problem in intensive care units (ICUs). The aim of this study was to describe the epidemiology of methicillin-resistant Staphylococcus isolates in a cardiac surgical ICU over a 5-year period and to determine the risk factors and outcome of this condition. METHODS During the period from January 1998 to July 2003, the clinical data of...