نتایج جستجو برای: methylprednisolone sodium succinate

تعداد نتایج: 198959  

Journal: :Japanese Journal of Pharmacology 1982

Journal: : 2023

The most common agent used for infusion therapy in patients with diabetic ketoacidosis (DKA) is isotonic 0.9% sodium chloride solution. However, of required volumes can result development iatrogenic complications — i. e., worsening metabolic hyperchloremic acidosis DKA already altered acid-base balance. Balanced crystalloid solutions be as alternative to saline. Objective. To evaluate the feasi...

Journal: :Journal of bacteriology 2009
Jung-Won Youn Elena Jolkver Reinhard Krämer Kay Marin Volker F Wendisch

Transporters of the dicarboxylate amino acid-cation symporter family often mediate uptake of C(4)-dicarboxylates, such as succinate or l-malate, in bacteria. A member of this family, dicarboxylate transporter A (DctA) from Corynebacterium glutamicum, was characterized to catalyze uptake of the C(4)-dicarboxylates succinate, fumarate, and l-malate, which was inhibited by oxaloacetate, 2-oxogluta...

Journal: :Terapevticheskii Arkhiv 2023

Aim. To evaluate the relationship between systemic inflammatory response and severity of COVID-19-associated endotheliopathy effect succinate-containing crystalloid solution (sodium meglumine succinate) on it in patients with severe COVID-19.
 Materials methods. Clinical laboratory parameters 53 intensive care unit's COVID-19 complicated by community-acquired bilateral multisegmental pneum...

Journal: :The Biochemical journal 2006
Felix Knauf Nilufar Mohebbi Carsten Teichert Diana Herold Blanka Rogina Stephen Helfand Maik Gollasch Friedrich C Luft Peter S Aronson

A longevity gene called Indy (for 'I'm not dead yet'), with similarity to mammalian genes encoding sodium-dicarboxylate cotransporters, was identified in Drosophila melanogaster. Functional studies in Xenopus oocytes showed that INDY mediates the flux of dicarboxylates and citrate across the plasma membrane, but the specific transport mechanism mediated by INDY was not identified. To test wheth...

Journal: :American journal of physiology. Renal physiology 2006
Yohannes Hagos Jürgen Steffgen Ahsan N Rizwan Denis Langheit Ariane Knoll Gerhard Burckhardt Birgitta C Burckhardt

In the present study, we determined the functional role of 15 positively charged amino acid residues at or within 1 of the predicted 11 transmembrane helixes of the flounder renal sodium-dicarboxylate cotransporter fNaDC-3. Using site-directed mutagenesis, histidine (H), lysine (K), and arginine (R) residues of fNaDC-3 were replaced by alanine (A), isoleucine (I), or leucine (L). Most mutants s...

2001
K. NIKOLICH C. SERGIDES A. PITTAS

Near Infrared Reflectance Spectroscopy (NIRS), coupled with fiber optic probes, has been shown to be a quick and reliable analytical tool for quality assurance and quality control in the pharmaceutical industry, both for verifications of raw materials and quantification of the active ingredients in final products. In this paper, a typical pharmaceutical product, hydrocortisone sodium succinate,...

2016
N.J. Olby A.C. Muguet‐Chanoit J.‐H. Lim M. Davidian C.L. Mariani A.C. Freeman S.R. Platt J. Humphrey M. Kent C. Giovanella R. Longshore P.J. Early K.R. Muñana

BACKGROUND Acute intervertebral disk herniation (IVDH) is a common cause of spinal cord injury in dogs and currently there is no proven medical treatment to counter secondary injury effects. Use of methylprednisolone sodium succinate (MPSS) or polyethylene glycol (PEG) as neuroprotectants is advocated but controversial because neither treatment has been tested in placebo-controlled, randomized,...

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