RATIONALE coronary artery ligation to induce myocardial infarction (MI) in mice is typically performed by an invasive and time-consuming approach that requires ventilation and chest opening (classic method), often resulting in extensive tissue damage and high mortality. We developed a novel and rapid surgical method to induce MI that does not require ventilation. OBJECTIVE the purpose of this...

Rationale: Coronary artery ligation to induce myocardial infarction (MI) in mice is typically performed by an invasive and time-consuming approach that requires ventilation and chest opening (classic method), often resulting in extensive tissue damage and high mortality. We developed a novel and rapid surgical method to induce MI that does not require ventilation. Objective: The purpose of this...

Objective(s): Despite several proposed mechanisms for the pathophysiology of cardiorenal syndrome (CRS), the exact mechanism remains unclear. Nitrosative stress has been argued as a key mechanism recently. Nebivolol is a beta-blocker with nitric oxide (NO)-releasing effect. In the present study, NO-mediated effects of two different treatment regimes of nebivolol in CRS...

a case-control study was performed by the research center of isfahan university, to determine the predisposing factors of early atherosclerosis. children of cases admitted to a university hospital in isfahan with early myocardial infarction (mi) were considered for the study. the affeckted cases (n=116), had 120 children aged 2-14 years. the control group were selected from children of the neig...

BACKGROUND Arrhythmia is the foremost cause of sudden death after myocardial infarction (MI). Animal models have recently shown that erythropoietin (EPO) can reduce the incidence of arrhythmia after MI. METHODS We investigated the effects of administrating 33,000 IU EPO on the occurrence of post-MI arrhythmia in 40 patients with ST-elevation MI who were randomly assigned in either EPO or plac...

Purpose: This PhD study explores the perspectives and experiences of people who do not use existing cardiac resources following a myocardial infarction (MI)y‘heart attack’, and of their family membersyfriends. How might the system of post-MI support be improved to help more people care for their heart instead of ‘voting with their feet’? Background: A large proportion of post-MI people, and par...

BACKGROUND The location of acute myocardial infarction (MI) is an important prognostic factor for risk stratification of patients with first ST-segment elevation MI (STEMI). The main goal of this study was to compare the severity and extension of coronary involvement in inferior and anterior MI. METHODS This study reviewed angiographic reports of 579 patients with a first anterior wall STEMI ...