Detergents are a viable method for earwax removal. Specifically, bile salts such as cholate and deoxycholate, work well for this function especially when placed in alkaline solution provided by sodium phosphate in the presence of 0.1 M sodium chloride. In vitro studies reveal these agents to quickly penetrate earwax, as visualized by yellowish color of the solution and lack of cohesion of the r...

Abstract Background Nowadays combination therapy has become more popular due to their additional effect, synergistic effect and antagonistic effect. Any of these can influence the treatment profile. Combination is used treat some chronic diseases like diabetes, hypertension, cancer etc. But recently India banned fixed dose drug combinations increased chances adverse effects interactions. So it ...