Title: Respiratory-gated (4D) contrast-enhanced FDG PET-CT for radiotherapy planning of lower oesophageal carcinoma: feasibility and impact on planning target volume Authors: Andrew Scarsbrook ([email protected]) Gillian Ward ([email protected]) Patrick Murray ([email protected]) Rebecca Goody ([email protected]) Karen Marshall ([email protected]) Garry McDermott (garry.mcderm...

Background: One major challenge in brachytherapy is to verify the accuracy of dose distributions calculated by the treatment planning system. In this project, a new phantom design has been introduced for quality assurance of dose distributions in gynocological (GYN) brachytherapy implants using EBT GafChromic film. Materials and Methods: This phantom has been designed and fabricated from 90 sla...

PURPOSE To investigate the clinical usage of dose verification of Helical Tomotherapy plans by using 2D-array ion chambers, and to develop an efficient way to validate the dose delivered for the patients during treatments. MATERIALS AND METHODS A pixel-segmented ionisation chamber device, IMRT MatriXX™ and Multicube™ phantom from IBA were used on ten selected Tomotherapy IMRT/IGRT head and ne...

BACKGROUND 2-step intensity modulated arc therapy (IMAT) is a simplified IMAT technique which delivers the treatment over typically two continuous gantry rotations. The aim of this work was to implement the technique into a computerized treatment planning system and to develop an approach to optimize the segment weights and widths. METHODS 2-step IMAT was implemented into the Prism treatment ...

We propose a strategy of individualized image acquisitions and treatment planning for respiratory-gated carbon-ion therapy. We implemented it in clinical treatments for diseases of mobile organs such as lung cancers at the Gunma University Heavy Ion Medical Center in June 2010. Gated computed tomography (CT) scans were used for treatment planning, and four-dimensional (4D) CT scans were used to...

Introduction: In recent years, the use of magnetic resonance (MR) images in radiation treatment planning has drawn considerable attention. However, although the extent of a tumor can be determined in great detail on MR images, the geometric accuracy of these images is limited by distortions stemming from the inhomogeneity of the static background magnetic field, the nonlineari...

PURPOSE To compare low dose volume and integral dose of various rotational arc radiation therapy modalities, including helical tomotherapy (HT) and other volumetric modulated arc therapies (VMAT). METHODS A digital cylindrical phantom and an anthropomorphic pelvic phantom were used in the study. HT treatment was planned on TomoTherapy Planning Station (Accuray) and VMAT plans were generated o...

An anthropomorphic head phantom, constructed from a water-equivalent plastic shell with only a spherical target, was modified to include a nonspherical target (pituitary) and an adjacent organ at risk (OAR) (optic chiasm), within 2 mm, simulating the anatomy encountered when treating acromegaly. The target and OAR spatial proximity provided a more realistic treatment planning and dose delivery ...

Introduction: Lung cancer is one of the most common causes of cancer-related deaths worldwide. Nowadays PET/CT plays an essential role in radiotherapy planning specially for lung tumors as it provides anatomical and functional information simultaneously that is effective in accurate tumor delineation. The optimal segmentation method has not been introduced yet, however several ...

The clinical use of respiratory-gated radiotherapy and the application of intensity-modulated radiotherapy (IMRT) are 2 relatively new innovations to the treatment of lung cancer. Respiratory gating can reduce the deleterious effects of intrafraction motion, and IMRT can concurrently increase tumor dose homogeneity and reduce dose to critical structures including the lungs, spinal cord, esophag...