Past discussions of the relative strengths of nested case-control and case-cohort designs have not fully considered cohorts with stored biological samples in which biomarker analyses are planned. Issues related to biomarker analyses can affect an investigator's choice of design and the conduct of these two designs. The key issues identified are effects of analytic batch, long-term storage, and ...

Complex event processing (CEP) over event streams has become increasingly important for real-time applications ranging from health care, supply chain management to business intelligence. These monitoring applications submit complex event queries to track sequences of events that match a given pattern. As these systems mature the need for increasingly complex nested sequence query support arises...

Transformation of nested SQL queries into join queries is advantageous because a nested SQL query can be looked upon as a nested-loop join, which is just one of the several join implementations that may be available in a relational DBMS. In join queries, dangling (unmatched) operand tuples are lost, which causes a problem in transforming nested queries having the aggregate function COUNT betwee...

The main objective of this paper is to provide experimental designs for the estimation of fixed effects and two variance components, in the presence of nested random effects. Random nested factors arise from quantity designations such as lot or batch, and from sampling and measurement procedures. We introduce a general class of designs for mixed-effects models with random nested factors, called...

BACKGROUND Ectopic adrenocorticotropic hormone-producing primary liver tumors are rare, especially in children. We report the case of an adolescent boy of mixed Dutch and Moroccan descent with an adrenocorticotropic hormone-producing calcifying nested stromal-epithelial tumor with long-term follow-up. Thus far, only two such cases have been reported. CASE PRESENTATION A 16-year-old boy of mix...

Nested words provide a natural model of runs of programs with recursive procedure calls. The usual connection between monadic second-order logic (MSO) and automata extends from words to nested words and gives us a natural notion of regular languages of nested words. In this paper we look at some well-known aspects of regular languages – their characterization via fixed points, deterministic and...

Stair nesting allows us to work with fewer observations than the most usual form of nesting, the balanced nesting. In the case of stair nesting the amount of information for the different factors is more evenly distributed. This new design leads to greater economy, because we can work with fewer observations. In this work we present the algebraic structure of the cross of balanced nested and st...

In a nested case-control study, controls are selected for each case from the individuals who are at risk at the time at which the case occurs. We say that the controls are matched on study time. To adjust for possible confounding, it is common to match on other variables as well. The standard analysis of nested case-control data is based on a partial likelihood which compares the covariates of ...

A network in which sensors observe a common Gaussian source is analyzed. Using a fixed linear transform, each sensor compresses its high-dimensional observation into a low-dimensional representation. The latter is provided to a central decoder that reconstructs the source according to a mean squared error (MSE) distortion metric. The Distributed Karhunen-Loève Transform (d-KLT) has been shown t...