The inflammatory hypothesis of depression is one of the main theories that endeavors to explain and describe the underlying biological mechanisms of depression and suicide. While mounting evidence indicates altered peripheral and central inflammatory profiles in depressed patients and suicide completers, little is known about how peripheral and central inflammation might be linked in these cont...

The hallmark of Parkinson Disease (PD) is the degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNc) and the consequent striatal dopamine (DA) deficiency, although it is well recognized that neurodegeneration in PD goes beyond the SNc. Major advances have occurred in recent years on the molecular and pathophysiological basis of PD, however there remain many questions a...

Vincent Geenen received the MD (1982) and PhD (1987) degrees from the University of Liege Medical School in Belgium. He is currently Research Director for the National Fund of Scientific Research of Belgium (NFSR), Chairman of the Center of Immunology at University of Liege, Professor of Developmental Biology at Liege Faculty of Sciences, Professor of History of Biomedical Research at Liege Med...

Elevated mortalities of brown trout (Salmo trutta m. fario) and grayling (Thymallus thymallus) were noticed in the Cetina River at the end of the February. Local anglers collected the samples of moribund fish and submitted them to the laboratory for examination. Ectoparasitological, bacteriological and virological examination did not reveal any ectoparasite, bacteria or viral agents, however py...

how to cite this article: najafi mr, najafi ma, nasr z. diagnosis and management of multiple sclerosis in children. iran j child neurol. summer 2016; 10(3): 13-23. abstract growing evidence indicates the safety and well toleration of treatment by disease-modifying in children suffering multiple sclerosis (ms). the treatment is not straight forward in a great number of patients, thus patients wi...