background previous studies using pegylated interferon (peg-ifn) and ribavirin (rbv) combination therapy suggested that patients with hepatitis c virus (hcv) genotype 1 and low pretreatment hcv rna level who achieved rapid virological response (rvr) can be treated for 24 weeks without compromising sustained virological response (svr) rate. objectives the current study aimed to investigate the e...

Treatment of bone metastases comprises over 10% of the workload of a radiation-oncology center. Bone metastases produce severe pain and immobility, necessitate narcotic use, and reduce the quality of life. A good palliative treatment must be complete, free from side effects and fast; Thus we decided to evaluate Strontium-89 (89Sr) effectivity for palliation of breast and prostate cancer b...

in daily life, complexity results from countless factors. culture, environment, social and economic status and physical ability all contribute, and all complicate managing ill health. pharmacists bear witness to many of these complexities and increasingly must care for what have come to be known as ‘complex patients’.  the issue of  ‘complex patients’ is one that has been addressed by healthcar...

twenty patients with bulky (>4 cm size) figo stage ib cervical cancer were treated with cisplatin 50 mg/m2 and vincristine 1 mg/m2, administered intravenously at 10-day intervals for a total of 3 courses before radical hysterectomy. a complete clinical response was noted in 1 patient (5%) and partial response in 5 (25%). fourteen patients (70%) had stable disease. there was no grade 3 toxicity ...

Twenty patients with bulky (>4 cm size) FIGO stage IB cervical cancer were treated with cisplatin 50 mg/m2 and vincristine 1 mg/m2, administered intravenously at 10-day intervals for a total of 3 courses before radical hysterectomy. A complete clinical response was noted in 1 patient (5%) and partial response in 5 (25%). Fourteen patients (70%) had stable disease. There was no grade 3 toxic...

background: the goal of antivenom administration for snake-bitten patients is to achieve therapeutic response (initial control), which means reversal of the venom-induced effects through neutralizing the venom. the aim of this study was to identify snakebite prognostic factors of weak therapeutic response prior to antivenom administration. methods: this was a retrospective study of patients wit...

n-terminal pro β-type natriuretic peptide (nt-probnp) is a valuable marker for monitoring the response to treatment in patients with heart failure. based on the clinically observed improvement of heart failure symptoms early after cardiac resynchronization therapy (crt), we sought to investigate whether crt induce any significant reduction in the plasma level of nt-probnp in three days after im...

Background: The goal of antivenom administration for snake-bitten patients is to achieve therapeutic response (initial control), which means reversal of the venom-induced effects through neutralizing the venom. The aim of this study was to identify snakebite prognostic factors of weak therapeutic response prior to antivenom administration. Methods: This was a retrospective study of patients wit...