Paul Conduit was a research assistant in John Kilmartin's lab at the MRC/LMB in Cambridge, UK, before beginning his PhD in 2006 with Jordan Raff. In 2010 he moved with Jordan from the Gurdon Institute in Cambridge to the University of Oxford, where he continued his work as a postdoctoral fellow. Paul is now a Sir Henry Dale Wellcome Fellow at the University of Cambridge and has been a group lea...

Abstract. Active subspaces can effectively reduce the dimension of high-dimensional parameter studies enabling otherwise infeasible experiments with expensive simulations. The key components of active subspace methods are the eigenvectors of a symmetric, positive semidefinite matrix whose elements are the average products of partial derivatives of the simulation’s input/output map. We study a M...

In spite of recent advances in supportive management and prevention of stroke, it is not uncommon to hear nonneurologists as well as neurologists express the opinion that "nothing can be done for a patient with a stroke." These individuals are expressing an attitude of therapeutic nihilism. The word nihilism is derived from the Latin nihil, meaning "nothing." A therapeutic nihilist is one who s...

Food quality is a topic of utmost importance as more and emphasis placed on rather than quantity products. Previous studies have pointed out the interaction with harvest year. In this study, 22 Pistacia vera (Greek ‘Aegina’ variety) samples (11 from 2017 11 2018) were differentiated using Fourier transform infrared spectroscopy (FTIR) (a) diffuse reflectance (DRIFTS) (b) KBr/sample disk techniq...

Portfolio implementation is critical for investment success. Seemingly minor differences in portfolio construction can lead to major differences in performance outcomes. In this paper, we summarize the differences between two popular portfolio construction approaches, “mix” and “integrate,” and examine a handful of value and momentum-themed examples to demonstrate how these differences play out...

S. B. Thakur, D. D. Dershaw, D. Giri, J. Zheng, C. Moskowitz, J. Ferrara, J. A. Koutcher, and E. A. Morris Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States, Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States, Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, United States, Epidemiology-Biostatistics, Memorial Sloan K...

one of the importants questions in the discourse of valery, french author of xxth century is the question of another who achieves in the knowledge. another is treated with a new way. indeed, another is defines in touch with the me of the author. that is the reflection of me and a dialectic becomes established between both: me and another. in his discourse, the enonciataire is in front of two in...