OBJECTIVE This paper presents the results of a clinical study assessing the in vivo effects on plaque metabolism of a new dentifrice containing 1.5% arginine, an insoluble calcium compound, and 1450 ppm fluoride compared to a commercially available dentifrice containing 1450 ppm fluoride alone. METHODS A four-week, parallel, randomized, double-blind clinical study using 54 subjects was conduc...

Most adults brush and floss inadequately, and constant education and/or reinforcement is often required. Bacteria are usually left behind with mechanical oral health routines, and chemotherapeutic agents may have a key role as adjuncts to daily home-care. To date, two antiseptic mouthwashes have received the ADA Seal of Acceptance: Peridex (Zila Pharmaceuticals, Phoenix, AZ, USA; CHX, chlorhexi...

The effect of plaque control on gingivitis and periodontitis is well-documented. In short-term investigations, chemical plaque control (oral rinsing twice a day with 0.2% chlorhexidine-gluconate solution) has been effective in the prevention of human gingivitis. Experimentally produced human gingivitis heals completely within one week when the same method is employed. Tooth cleaning with oral h...

OBJECTIVES Atherosclerosis is chronic inflammatory process triggered by oxidative stress. Oxidative stress can increase hydrogen peroxide (H2O2) level, which induce atherosclerosis through the processes such as formation of perivascular adipose tissue (PVAT), foam cells, and atherosclerotic plaque. Antioxidant is needed to control negative effects of oxidative stress. One source of antioxidant,...

Dental researchers have attempted to understand the microbial nature of oral diseases over the past 120 years. Their view of plaque and its constituent microorganisms has shifted from a specific plaque hypothesis to a non-specific plaque hypothesis and back again to a theory of specific periodontal pathogens in plaque. Changes in the way plaque and its microorganisms are viewed affect the strat...

Plaque formation can be controlled either chemically or mechanically. Chemical plaque removal suffers lots of disadvantages like chemical agent can't penetrate the biofilm or the amount of agent which has penetrated is very less to kill bacteria present and also long term use of chemical plaque control agents can lead to staining of teeth. So, mechanical removal of supragingival plaque remains ...

in the present study, variation among different bacterial strains was observed in the plaques of tobacco chewers (tc) as compared to those from normal persons (non tobacco chewers) (ntc). bacterial strain j1 (dominant in the plaques of ntc) did not initiate the process of adhesion (biofilm formation) until it appeared to have reached a required population density necessary for the production of...

Introduction: Mangosteen, a fruit indigenous to tropical rainforest regions such as Southeast Asia, has been used key component in Chinese medicine and Ayurveda. It possesses antibacterial, anti-plaque, anti-inflammatory properties. While chlorhexidine mouthwash is considered the gold standard, its multiple side effects necessitate search for an herbal substitute.Aim: To evaluate anti-plaque ef...

Objective: To study and analyse changes of serum CXCL12 in patients with acute cerebral infarction and its clinical significance. Methods: According to diagnosis criteria and exclusive conditions, 60 patients with acute cerebral infarction first had been diagnosed by clinic were recruited as experimental group. 60 healthy physical examination whose clinical indexes had no statistical difference...