peptide and protein drugs have found an important position in therapeutics. recent advances in pharmaceutical biotechnology have led to an increase in the number of protein products in the market. as these therapeutic proteins and peptides are made available, it will be essential to formulate these drugs into safe and effective delivery systems. the twenty different naturally occurring amino ac...

abstract lettuce is one of the best accumulators of heavy metals and nitrate between leafy vegetables. through this research, it was tried to decreased cadmium absorption with humic acid (ha) and studies the effect of ha on the accumulation and metabolism of nitrate. plants were grown in the peat/perlite and irrigated with hoagland solution with addition of cadmium (2 and 4 mg l -1) and ha (100...

The nutritional factors which affect lead absorption have been studied. Synthetic diets of known composition were compounded to contain 0-075% Pb as PbCl2 labelled with 203Pb. Rats were exposed to lead for periods of 48 hr. The dietary intake was then measured and the absorption of lead determined by means of a whole-body counter. Lead absorption was increased by high fat, low mineral, low prot...

Li, Tianbo, and Hans G. Folkesson. RNA interference for -ENaC inhibits rat lung fluid absorption in vivo. Am J Physiol Lung Cell Mol Physiol 290: L649–L660, 2006. First published October 28, 2005; doi:10.1152/ajplung.00205.2005.—We used siRNA against the -ENaC (epithelial Na channel) subunit to investigate ENaC involvement in lung fluid absorption in rats by the impermeable tracer technique dur...

High dietary protein intakes are known to increase urinary calcium excretion and, if maintained, will result in sustained hypercalciuria. To date, the majority of calcium balance studies in humans have not detected an effect of dietary protein on intestinal calcium absorption or serum parathyroid hormone. Therefore, it is commonly concluded that the source of the excess urinary calcium is incre...

In order to investigate the effect of drought stress and application chemical biological fertilizers potassium maize cultivars on micronutrient uptake, protein content, proline changes, an experiment was conducted as a split-plot based randomized complete block design with three replications. The main factor levels treatment, irrigation, irrigation cut at 12 leaf stage flowering stage; first su...

A theory of radiation absorption by dielectric mixtures is presented. The coarse-grained formulation is based on the wave-vector-dependent correlation functions of molecular dipoles of the host polar liquid and a density structure factor of the solutes. A nonlinear dependence of the dielectric absorption coefficient on the solute concentration is predicted and originates from the mutual polariz...

The aim of this account is to summarize current views on the absorption of the products of protein digestion, amino acids and peptides. Longer reviews of protein absorption (Wiseman, 1968; Matthew, 1969, 1971; Gray & Cooper, 1971) will provide references not given here. Hormonal effects on absorption are reviewed by Levin (1969). Protein digestion is initiated in the stomach by pepsins and cont...

The delivery of therapeutic proteins has gained momentum with development of biotechnology. However, large molecular weight, hydrophilic nature and susceptibility to harsh environment of gastrointestinal tract (GIT) resulted in low absorption. The main objective of this work was the design of a particulate system for oral delivery of recombinant human growth hormone (rhGH) on the basis of parti...