BACKGROUND Atrial fibrillation (AF) may recur after pulmonary vein isolation (PVI) as the result of either recurrent PV conduction or non-PV foci. This study characterized the electrophysiological findings of patients with recurrent AF after initially successful PVI and the clinical outcome after a repeat procedure. METHODS AND RESULTS Among 185 patients undergoing PVI, 52 reported no signifi...

BACKGROUND The clinical relevance of the degree of peritumoral vascular invasion (PVI) in patients with no or limited involvement of the axillary nodes is unknown. MATERIALS AND METHODS 2606 consecutive patients with pT1-3, pN0 (1586)-1a (1020) and M0, operated and counseled for medical therapy from 1/2000 to 12/2002, were prospectively classified according to the degree of PVI: absent (2017,...

Paranjape, Vaidehi V. M.S., Purdue University, August 2014. Clinical Investigation of Plethysmographic Variability Index: A Derivative Index of Pulse Oximetry in Anesthetized Dogs. Major Professor: Jeff C. Ko. Plethysmographic Variability Index (PVI) is a derivative index of pulse oximetry that allows evaluating an individual's intravascular volume status. Perfusion Index (PI) represents the st...

AIMS Cerebral embolism is a possible serious complication during catheter ablation of atrial fibrillation (AF). The purpose of this prospective pilot study was to analyse the incidence and possible impact of cryo ablation on cerebral lesions and possible differences to radiofrequency (RF) ablation during pulmonary vein isolation (PVI). METHODS AND RESULTS Pulmonary vein isolation was performe...

BACKGROUND To prevent atrial fibrillation (AF) recurrence after catheter ablation, pulmonary venous isolation (PVI) at an antral level is more effective than segmental ostial ablation. Cryoablation around the pulmonary venous (PV) ostia for AF therapy is potentially safer compared to radiofrequency ablation (RFA). The aim of this study was to investigate the efficacy of a strategy using a large...

We tested the hypothesis that phosphodiesterase type 5 inhibitor (PDE5i) use would be associated with increased likelihood of condom breakage using an event-specific analysis. A convenience sample of 440 men completed an internet-based questionnaire that assessed variables pertaining to the last time they used condoms for penile-vaginal intercourse (PVI). A bivariate (screening) analysis was pe...

The present study aimed to evaluate the procoagulant effects of phosphatidylserine (PS) exposure on blood cells and microparticles (MPs), and examine its role in predicting early recurrence atrial fibrillation (ERAF) in patients with atrial fibrillation (AF) treated with pulmonary vein isolation (PVI). Blood samples were obtained from 40 healthy controls and 56 patients with AF at baseline (pri...

A 79-year-old man with situs inversus and dextrocardia underwent catheter ablation of symptomatic paroxysmal atrial fibrillation. Pulmonary vein isolation (PVI), using second-generation cryoballoon under Ensite NavX system guidance, was performed successfully in a reverse manner, which required short procedure and fluoroscopy times, as required in a PVI performed on a normal heart without any c...

Current guidelines recommend using bivalirudin as an alternative to unfractionated heparin in patients with heparin-induced thrombocytopenia undergoing percutaneous coronary intervention (PCI). Pulmonary vein isolation (PVI) is a well-established treatment strategy for patients with drug-refractory atrial fibrillation (AF) and requires systemic anticoagulation to avoid thromboembolic events, ge...

Pulmonary vein isolation (PVI) is the cornerstone of catheter ablation for atrial fibrillation (AF), especially in paroxysmal 1 AF patients. In addition to a radiofrequency ablation catheter, a cryoballoon has been proven as an effective technology in PVI for AF. Recently several randomized trials have shown that cryoballoon ablation was noninferior to radiofrequency ablation with respect to ef...