Radiotherapy (RT) is generally considered to be one of the most effective cancer treatments. The primary goal of RT is to accurately induce radiation damage to the tumor while limiting radiation toxicity to a level acceptable to normal tissue. This is accomplished by targeting the tumor with radiation. On the other hand, the status of RT procedures as they stand today is not substantial enough ...

background: the rationale was to develop an ablation approach to destroy regions of tumor resistant to radiation and thus reduce the time required for whole tumor ablation, while improving overall tumor control after radiotherapy. materials and methods: the system is composed of a micro positron emission tomography (mpet), 7t magnetic resonance imaging (mri), and a customized mri-compatible foc...

Recent advances have improved the effectiveness, decreased the complications, and expanded the implications of radiation therapy. These advances include three-dimensional conformal radiation therapy, intensity-modulated radiation therapy, stereotactic radiotherapy, brachytherapy, and radioimmunotherapy. Each of these modalities has improved radiation targeting, thereby limiting radiation exposu...

Introduction: Many study shown the effectiveness dose enhancement with gold nanoparticles (GNPs), especially with low-energy x-rays. Recently, proton beam radiation therapy (PBRT) has attention as a treatment for tumors. The advantage in PBRT, which releases high dose at the controllable Bragg peak position that localized for Au target and the released dose increased in depth....

Introduction: The current study aimed to compare the performance of radiobiological models in predicting acute esophagitis (AE) complications after three-dimensional conformal radiation therapy (3D-CRT). Material and Methods: Out of a total of 100 patients, 50 patients with concurrent chemotherapy and 50 patients without such therapy wer...

In recent years, the use of gold nanoparticles (GNPs) in radiation therapy has been studied by experimentation and Monte Carlo simulation repeatedly. Although the idea of increasing doses has been raised by high-atomic elements since decades ago, but due to the adaptation of gold nanoparticles with the biological system, scientists have incited more about the various uses of these materials in ...

Radiation-gene therapy, a dual anticancer strategy of radiation therapy and gene therapy through connecting radiation-inducible regulatory sequence to therapeutic gene, leading to the gene being induced to express by radiation while radiotherapy is performed and finally resulting in a double synergistic antitumor effect of radiation and gene, has become one of hotspots in the field of cancer tr...

Introduction: External Beam Radiation Therapy (EBRT), a type of whole breast radiation therapy, has been widely used in patients with early-stage cancer, however it is associated longer treatment periods and higher toxicity.