The formation of long chain unsaturated fatty acids from the corresponding saturated acids in animals was established by the work of Schoenheimer and Rittenberg (1) and Stetten and Schoenheimer (2). Recent studies in this laboratory have shown that in yeast the formation of Ag-unsaturated fatty acids is catalyzed by an enzyme system acting on the coenzyme A derivatives of the corresponding satu...

The fatty acid growth requirements of a sterol-requiring Mycoplasma (strain Y), unable to synthesize or alter the chain length of either saturated or unsaturated fatty acids, were investigated. In some cases adaptation was required for growth when mycoplasmas were transferred to media of differing fatty acid composition. No straight-chain saturated acid supported growth when tested alone, but g...

We tested whether trans fatty acids and saturated fatty acids had different effects on flow-mediated vasodilation (FMD), a risk marker of coronary heart disease (CHD). Consumption of trans fatty acids is related to increased risk of CHD, probably through effects on lipoproteins. Trans fatty acids differ from most saturated fatty acids because they decrease serum high-density lipoprotein (HDL) c...

Straightor normal-chain, saturated components (even-numbered) make up 10-40% of the total fatty acids in most natural lipids. The most abundant saturated fatty acids in animal and plant tissues are straight-chain compounds with 14, 16 and 18 carbon atoms, but all the possible oddand even-numbered homologues with 2 to 36 carbon atoms have been found in nature in esterified form. They are named s...

The objective of this study was to investigate the antimicrobial activities of saturated fatty acids and fatty amines against methicillin-resistant Staphylococcus aureus (MRSA). The antimicrobial activity of saturated fatty acids and fatty amines was determined by oxygen meters with multi-channels and disposable oxygen electrode sensors (DOX-96). Lauric acid, the most effective among the satura...

The distributions of fatty acids in subcutaneous-adipose-tissue aspirates and their relation to intake as assessed by a semiquantitative food-frequency questionnaire were investigated in 115 postmenopausal US women free from cancer. Percentages of fatty acids in adipose tissue were significantly correlated with the percentage of total fat intake for polyunsaturated fatty acids (Spearman correla...

Palmitic, stearic, oleic, and linoleic acids at concentrations of 200 nmol/ml all inhibited autolysin activity 80% or more in whole cells or cell-free extracts. This concentration of the saturated fatty acids palmitic acid and stearic acid had little or no effect on the growth of whole cells or protoplasts. However, the unsaturated fatty acids oleic acid and linoleic acid induced lysis in both ...

The study was conducted to investigate the fatty acid profile of intramuscular fat in longissimus lumborum (LL) of three genotypic groups: Qazvinian native (Q, n=10), crossbred Qazvinian native × Saanen breed (QS, n=10) and backcrossed Qazvinian native × Saanen breed (QSS, n=9) male kids.All of kids were weaned at 75-days-old and then fed with a diet consisted of concentrate (70%) and alfalfa h...

dietary fatty acids play a critical role in modulation of airway inflammation in asthma. this study was conducted to compare dietary intakes of essential fatty acids and serum levels of inflammatory factors in asthmatic and healthy adults, and to examine the potential relationship between inflammatory markers and dietary fatty acids. in this case-control study, 47 asthmatic patients (26 males a...

Background: Co-supplementation of unsaturated fatty acids (FAs) with saturated FAs may decrease the adverse effects of saturated FA-induced lipotoxicity. The objective of the present study was to evaluate the effect of palmitoleic acid (unsaturated fatty acid) on palmitic acid (saturated fatty acid) induced lipotoxicity criteria in the primary culture of adult rat cardiomyocytes. Methods: Ce...