background and aims: diabetic nephropathy (dn) is the most common cause of end-stage renal failure which could increase the risk of cardiovascular disease and morbidity and mortality in patients. the aim of this study was to investigate new modalities for treatment of diabetic nephropathy. methods:this study was a mini-review research to investigate drugs that are used for dn treatment. results...

in this investigation wer studied the effect of dopaminergic system on the conflict behavior in rat, using vogel’s test. the related drugs were injected intraperitonealy (ip), and produced the following results:diazepam at doses of 0.5 and 1 mg/kg increased the lick –shock responses in the vogel’s thest. quinpirole (d2-agnosit), at doses of 0.1 and 10 mg/kg, increased the confict responses, whe...

rheumatoid arthritis is a chronic inflammatory disease characterized by the sequestration of various leukocyte subpopulations within both the developing pannus and synovial space. this study was undertaken to examine the therapeutic potency of tindurin in experimental rheumatoid arthritis. collagen-induced arthritis (cia) was induced by intradermally immunization of lewis rats at the base of th...

The thionamide drugs, i.e. carbimazole and its metabolite methimazole (MMI), andpropylthiouracil (PTU) have extensively been used in the management of various forms ofhyperthyroidism over the past eight decades. This review aims to summarize different aspectsof these outstanding medications. Thionamides have shown their own acceptable efficacy andeven safety profiles in ...

BACKGROUND The parasitic trematode Schistosoma mansoni is one of the major causative agents of human schistosomiasis, which afflicts 200 million people worldwide. Praziquantel remains the main drug used for schistosomiasis treatment, and reliance on the single therapy has been prompting the search for new therapeutic compounds against this disease. Our group has demonstrated that heme crystalli...

OBJECTIVE The schistosomicidal properties of garlic (Allium sativum) and onion (Allium cepa) powder were tested in vitro against Schistosoma mansoni miracidia, schistosomula, cercaria and adult worms. Results indicate their strong biocidal effects against all stages of the parasite and also show scavenging inhibitory effect on 2,2-diphenyl-1-picrylhydrazyl (DPPH) and nitric oxide (NO). MATERI...

Schistosomiasis, generally identified as Bilharzia, is an earliest human disease, Schistosoma mansoni is transmitted by the aquatic pulmonate snails of the genus Biomphalaria. Intestinal schistosomiasis due to infection with Schistosoma mansoni have been known in Saudi Arabia. Also, the urinary schistosomiasis has been reported in Saudi Arabia since 1887, absolutely certain members of the genus...

background & aim: in recent years, complementary therapies deliver a medicinal drop named ‘dentol’ for pain controlling and tooth infection. according to the excessive consumption of chemical drugs and their side effects, the subject of human health and its development in society and the level of awareness, insight and positive behavior of people and also dentists as the trustees of the soc...

case: a 26-year-old man referred to emergency service with coma, bradypnea (respiratory rate = 4 breaths per minute) and pinpoint pupil. on chest auscultation, diffuse coarse crackle and on abdominal auscultation, decrease of abdominal sounds were found. at first evaluation, pulse oximetry showed 19% saturation of oxygen. after oxygen therapy with facial mask and infusion of 8.4 mg naloxone in ...