The postnatal maturation of the human prefrontal cortex is associated with substantial increase of number of oligodendrocytes. Previously, we reported decreased numerical density of oligodendrocytes in the prefrontal cortex in schizophrenia and mood disorders. To gain further understanding of the role oligodendrocytes in pathogenesis of schizophrenia and mood disorders, we examined the effect o...

patients and methods the study sample included 50 patients with schizophrenia in tuba rehabilitation center in ardabil selected by available sampling method. healthy group participants were selected through cloning by age, gender and marital status of the patient group. the data were collected by the questionnaire of holmes-rahe scale and cohen et al. data were analyzed by multivariate anova (m...

Aim: The sharing about an important public health problem, schizophrenia is increasing on Twitter, whiches user number multiplies day by day. Stigmatization can be usually met in the disorder of complex etiology. In this study, we aimed to investigate perspectives and attitudes community toward schizophrenia, schizopherene, schizophrenic, paranoiac social media -Twitter- Turkey. Material Method...

Objective: The relationship between obsessive compulsive disorder and schizophrenia has been a matter of dispute for ages. This study aimed to investigate the differences between schizophrenia with obsessive compulsive symptoms (OCS) and schizophrenia without OCS in affecting positive and negative symptoms of schizophrenia.  Methods: Study participants comprised 30 patients with schizophr...

This research studied hypotheses that positive thought disorder in schizophrenia is influenced by patients' not taking in immediate target contextual material, thereby losing vital cues that guide thought processes. We assessed 164 acute inpatients (including 55 schizophrenia and 31 bipolar disorder patients), using standardized measures of thought disorder. We also used new measures that asses...

BACKGROUND Attention-deficit hyperactivity disorder (ADHD) is associated with bipolar disorder and schizophrenia, and it has been suggested that combined bipolar disorder and ADHD is aetiologically distinct from the pure disorders. AIMS To clarify whether ADHD shares genetic and environmental factors with bipolar disorder and schizophrenia. METHOD By linking longitudinal Swedish national re...

Individuals with schizophrenia have significant deficits in premorbid social and academic adjustment compared to individuals with non-psychotic diagnoses. However, it is unclear how severity and developmental trajectory of premorbid maladjustment compare across psychotic disorders. This study examined the association between premorbid functioning (in childhood, early adolescence, and late adole...

Paliperidone is an atypical antipsychotic medication commonly used to treat schizophrenia, schizoaffective disorder, and bipolar disorder. It a metabolite of risperidone has similar mechanism action, primarily blocking dopamine 2 receptors (D2 receptors) in the brain. various adverse effects, including extrapyramidal symptoms, weight gain, metabolic disturbances. Catatonia rare but severe side ...