It is acknowledged that local and systemic inflammatory processes play an important role in the development and progression of atherosclerotic lesions, and in the pathophysiology of acute coronary syndromes. Established cardiovascular risk factors do not completely explain the epidemiological changes of, and the diverse presentations of, coronary heart disease. This had led to increasing intere...

Dengue virus (DENV) is the world most prevalent mosquito-transmitted virus. The incidence of dengue infection has been increasing and most of the infected people are asymptomatic or have non specific febrile illness. Laboratory test is essential to confirm dengue infection in epidemiological studies. We developed an indirect ELISA test based on monoclonal immunoglobulin against all four DENV se...

Approved: ____________________________________ Thesis Supervisor ____________________________________ Title and Department ____________________________________ Date 1 A SEROEPIDEMIOLOGICAL STUDY OF CANINE ZOONOSES AMONG PERSONS OCCUPATIONALLY EXPOSED TO DOGS by Whitney Sue Krueger A thesis submitted in partial fulfillment of the requirements for the Doctor of Philosophy degree in Epidemiology i...

Although the dengue iceberg phenomenon is well known, there is a paucity of data on inapparent dengue. Results from a seroepidemiological study conducted during a dengue epidemic in 2007 in Singapore showed a seroprevalence of 65.9% and an inapparent dengue rate of 78%. Older adults (> 45 years old) had significantly higher rates of inapparent dengue infections (P < 0.05).