نتایج جستجو برای: shuttle
تعداد نتایج: 6930 فیلتر نتایج به سال:
Observations on systems reconstituted in vitro with different starting substrates (2-hydroxy-acids, 2-oxo-acids or leucine) indicate that a branched-chain 2-hydroxy-acid/2-oxo-acid shuttle for the transfer of reducing equivalents from cytosol to mitochondria may be operational in mouse sperm. Evidence is presented suggesting that the 2-oxo-acids produced by intramitochondrial oxidation of 2-hyd...
In this work, we have investigated a novel distal proton shuttle mechanism of ribosome catalyzed peptide bond formation reaction. The reaction was found to follow a two-step mechanism. A distal water molecule located about 6.1 Å away from the attacking amine plays as a proton acceptor and results in a charge-separated intermediate that is stabilized by the N terminus of L27 and the A-site A76 5...
This study demonstrates the effectiveness of a peptide shuttle in delivering diclofenac into and through human epidermis. Diclofenac was conjugated to a novel phenylalanyl-N-methyl-naphthalenylalanine-derived diketopiperazine (DKP) shuttle and to TAT (a classical cell penetrating peptide), and topically applied to human epidermis in vitro. DKP and TAT effectively permeated into and through huma...
Background: Today, several vaccines have been developed to prevent infectious diseases. The older first-generation vaccines may have many problems. In this regard, genetic engineering plays an important role using tools such as shuttle vectors to develop recombinant DNA vaccines that usually include plasmid constructed so that can propagate in two different host species. The present study revie...
Mars and beyond is no longer science fiction. Through shuttle research we know how the body changes, what we need to do to fix some of the problems or—better yet—prevent them, the importance of monitoring health, and how to determine the human body's performance through the various sequences of launch, spaceflight, and landing. Basically, we understand how astronauts keep their performance high...
Multi shuttle automated storage retrieval systems have been developed for use in factories and distribution centers since they are more e cient than single shuttle systems due to less empty travel This improved e ciency results in more agile support exible response less waiting time etc for the production system the storage retrieval system serves In this paper we develop analytical models to e...
The present study compared the memory of young and older adults for details pertaining to two public events of close temporal proximity but varying emotional import-the Columbia shuttle explosion and the 2003 Super Bowl. Participants responded to surveys sent within 2 weeks of these events and then again 7 months later, providing information about event-related details (i.e., of the events them...
We present a method for calculating the full current noise spectrum S(ω) for the class of nano-electromechanical systems (NEMS) that can be described by a Markovian generalized master equation. As a specific example we apply the method to a quantum shuttle. The noise spectrum of the shuttle has peaks at integer multiples of the mechanical frequency, which is slightly renormalized. The renormali...
The mask set for a shuttle run (multi-project wafer) may contain designs using different number of metal layers. Wafers fabricated with k metal layers can only yield dice for the designs using only k metal layers. This results in considerable waste of wafers. In this paper we propose a simple concept called Lifted-I/O (LIO) to address this problem. LIO elevates the I/Os of all designs to the hi...
بررسی مقایسه ای پنج آزمون عملکردی اندام تحتانی در بیماران با پارگی لیگامان متقاطع قدامی و افراد سالم
این پژوهش بصورت غیرتجربی و توصیفی - تحلیلی با هدف بررسی مقایسه ای پنج آزمون عملکردی اندام تحتانی در دو گروه بیماران با پارگی لیگامان متقاطع قدامی و افراد سالم انجام شد. دراین تحقیق از پنج آزمون عملکردی زیر استفاده گردید: 1 - آزمون co-contraction semicircular . 2- آزمونcarioca . 3 - آزمون shuttle run . 4- آزمونtimed hop . 5- آزمون cross-over hop .
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