Background: Breast cancer is the second leading cause of death in women developing countries. The activity Warburg and Reverse-Warburg effects on breast reflected by expression patterns two molecules, namely caveolin-1 Monocarboxylate Transporter-4 (MCT-4). MCT-4 a transmembrane transport protein that transports lactate from cytoplasm to intercellular fluid.Method: This cross-sectional analytic...

rice plants are injured at the seedling stage in early spring in northern iran. in order to study rice response to cold stress, the expression of osdreb1a, osap37, osmyb3r-2, and osnac6 genes encoding transcription factors was observed in 14-day-old seedlings of cold-tolerant genotype pr and cold-sensitive cv. hashemi during cold stress (5°c for 24 h) using the differential display method and t...

objective(s):  cd44 is a member of the cell adhesion molecules family. naturally, cd44s, along with cd44v3 influence the cell motility, migration, and adhesion, while in tumor cells they lead to tumor invasion, progression, and metastasis. the purpose of this research is to evaluate the cd44s and cd44v3 expression in esophageal squamous cell carcinoma (escc) and to reveal their correlations wit...

background and objectives: presence of steroid hormone receptors (estrogen and progesterone) in the tumor tissues of various organs correlates with response to therapy and prognosis. since their role in ovarian cancer is still controversial, in this study we investigated the expression and prognostic value of the estrogen receptor (er) and progesterone receptors (pr) in ovarian papillary serous...

the response of plants to drought stress depends on several factors including the plant developmental stage and the length and severity of the stress applied. common bean (phaseolus vulgaris l.) is the most important pulse crop that is cultivated worldwide for human consumption. understanding of the mechanisms responsible for its response to drought is, therefore, essential. an increasing numbe...

objective her-2/neu gene is overexpressed in diverse human cancers and studies suggest a role of its product – p185 protein – in tumor progression by specifically promoting the invasive capacity of tumor cells. our aim was to evaluate her-2/neu content in resectable gastric cancer in this geographical region and assess the relationship between p185 expression and clinicopathologic tumor paramet...

Myelodysplastic syndromes (MDSs) are a clonal bone marrow (BM) disease characterized by ineffective hematopoiesis, dysplastic maturation and progression to acute myeloid leukemia (AML). Methylation silencing of HRK has been found in several human malignancies. In this study, we explored the association of HRK methylation status with its expression, clinical parameters and MDS subtypes in MDS pa...

myelodysplastic syndromes (mdss) are a clonal bone marrow (bm) disease characterized by ineffective hematopoiesis, dysplastic maturation and progression to acute myeloid leukemia (aml). methylation silencing of hrk has been found in several human malignancies. in this study, we explored the association of hrk methylation status with its expression, clinical parameters and mds subtypes in mds pa...