introduction: the hippocampus was recognized as an important focus of epileptic seizures. a long-term potentiation (ltp) like that of epileptiform activities is considered as synaptic which has been observed for the first time in hippocampal formation. the purpose of the present study was investigating the synaptic plasticity induced by tetanic stimulation at ca1 area of the rat hippocampal sli...

objectives: alzheimer’s disease causes many negative effects on the individual's physical, psychological and cognitive conditions. the multi sensory stimulation helps the patients to improve their physical, psychological and cognitive conditions. the aim of this study is to determine the effect of multi sensory stimulation on cognitive status and quality of life of the patients with alzhei...

Objective: Diabetic patients suffer from different types of complications associated with peripheral nerves. A clear manifestation of these complications is found in the mouth where neuropathies commonly occur. The measurement of electrical stimulation threshold of teeth signifies premature involvement of peripheral nerves in the teeth. The aim of present study is to compare pulp tester respons...

Introduction: Electrical low-frequency stimulation (LFS) has antiepileptic effect, but the role of different stimulation parameters on this effect has not been determined. In this study the effect of different LFS parameters (intensity, pulse duration and train duration) on piriform-cortex kindled seizures was investigated. Methods: Seizure was produced in animals using kindling model of ep...

advantages of mild-stimulation have long been appreciated, while there was a called for more patient-friendly approach in ovarian stimulation around 20 years ago (1)...

introduction: application of low-frequency stimulation (lfs) is a new method for treatment of drug resistant epileptic patients. previous studies demonstrated that activation of receptors coupled to gi proteins is one of the mechanisms of the anticonvulsant effect of lfs. thus, in this study, alterations in the expression of rgs4 and rgs10 proteins, as negative regulators of gi proteins, were i...

introduction: it is believed that locus coeruleus (lc) influences the sensory information processing. however, its role in cortical surround inhibitory mechanism is not understood. in this experiment, using controlled mechanical displacement of whiskers we investigated the effect of phasic electrical stimulation of lc on response of layer v barrel cortical neurons in anesthetized rat. methods: ...

background: poor ovarian response to controlled ovarian stimulation is one of the most important interest points in assisted reproduction. mild ovarian stimulation seems to be preferable to high dose of fsh regimens in women with a history of poor ovarian response in previous protocol. clomiphene citrate and letrozole alone or in combination with fsh have been used in mild ovarian stimulation p...

Introduction: Application of low-frequency stimulation (LFS) is a new method for treatment of drug resistant epileptic patients. Previous studies demonstrated that activation of receptors coupled to Gi proteins is one of the mechanisms of the anticonvulsant effect of LFS. Thus, in this study, alterations in the expression of RGS4 and RGS10 proteins, as negative regulators of Gi proteins, wer...