BACKGROUND Heart failure survival models typically are constructed using Cox proportional hazards regression. Regression modeling suffers from a number of limitations, including bias introduced by commonly used variable selection methods. We illustrate the value of an intuitive, robust approach to variable selection, random survival forests (RSF), in a large clinical cohort. RSF are a potential...

Cox proportional hazards (PH) regression is a well-known model for analyzing survival data and its strengths are widely recognized. Threshold regression (TR) is a relatively new methodology but one that is receiving greater attention and being used successfully by researchers in different fields, including biopharmaceutical statistics. In threshold regression, event times are modeled by a stoch...

The primary objective of this work was to investigate and compare the use of the Cox proportional hazards model and Aalen’s additive model in analysing survival data. Survival data from a study of 52 patients with advanced breast cancer was investigated using the Cox proportional hazards model. The model was optimized by examining different aspects by use of appropriate residual plots. Covariat...

Gu and Zheng (1993) established a Bartlett adjustment for the partial likelihood ratio test in the Cox proportional hazards regression model. It is known that the same method of adjustment cannot be used to improve the accuracy of the test statistic derived by Rao’s score method. In this paper, the method of Cordeiro and Ferrari (1991) is used to derive a Bartlett type correction for the score ...

A major assumption of the Cox proportional hazards model is that the effect of a given covariate does not change over time. If this assumption is violated, the simple Cox model is invalid, and more sophisticated analyses are required. This paper describes eight graphical methods for detecting violations of the proportional hazards assumption and demonstrates each on three published datasets wit...

Background: The age at first birth corresponds to the of mother giving child. study aims accessing determinants timing among Ethiopian women.
 Methods: data for this was extracted from published reports Demographic and Health Survey. used15, 683 women aged 15-49 years nine regions two city administrations. Cox Proportional hazards model used identifying factors associated with birth.
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The burden of cancer is increasing very rapidly day by all over the world, largely due to an unhealthy lifestyle. Some cross-sectional studies have been conducted on lifestyle patients based Sylhet city, Bangladesh. However, best our knowledge, no study has done longitudinal aspect considering whole Bangladesh, therefore, we aimed conduct a know effects and heritability in We selected total 384...