Background: Bioinformatic approaches for designing vaccines have become a promising alternative to conventional methods. We herein designed a multi-epitope-based vaccine against colorectal cancer (CRC). Methods: Used peptides in the CRC vaccines were retrieved from databases of PubMed, Web of Science, Google Scholar, and Clinical trials. The adjuvants of Mycobacterial heparin-binding hemagglut...

the complexity of urban systems in our recent world, make it difficult to evaluation and explanation of their changes with traditional and customarily methods. in the past, remote sensing has shown an ability to detect and describe urban growth patterns at different spatial scales. with new remote sensing devices (e.g. ikonos), with innovative image processing techniques and with further develo...

today we are facing with a turbulent world full of complexity and change. contemporary problems are too complicated for rational, logical solutions. they admit insights, not answers. chaos theory is a solution to reveal insights into the structure and the dynamics of complex systems. chaos theory is in formative stage, but we can use it in management practices. this article is about application...

Molecular dynamics simulation has been performed to analyze the effect of the presence of gold nanoparticle on dynamics of Kob-Anderson binary Lennard-Jones (BLJ) mixture upon supercooling within the framework of the mode coupling theory of the dynamic glass transition. The presence of gold nanoparticle has a direct effect on the liquid structure and causes the peaks of the radial distribution ...

Microtubule Affinity-Regulating Kinase 2 (MARK2) protein has a substantial role in regulation of vital cellular processes like induction of polarity, regulation of cell junctions, cytoskeleton structure and cell differentiation. The abnormal function of this protein has been associated with a number of pathological conditions like Alzheimer disease, autism, several carcinomas and development of...